Sort   by:  
 Page size 
ProteomicsProtein metabolism of Suaeda salsa
Suaeda salsa is a medicinal and edible plant.and the differentially expressed proteins were detected by tandem mass spectrometry (TMT) quantitative proteomics. A total of 4771 proteins were quantified, including 317 differentially expressed proteins (2.0-fold change, P < 0.05), of which 143 were up-...
ORGANISM(S): Chenopodiaceae 
2021-07-30 | PXD027682 |
ProteomicsSIRT5-Mediated FDX1 Desuccinylation Confers Cuproptosis Resistance in Lung cancer
Cuproptosis, a copper-dependent cell death process induced by excessive copper, represents an emerging therapeutic strategy in oncology. However, tumor specific molecular pathways regulating this process remain poorly defined. Here, we demonstrate that copper levels are elevated in lung adenocarcino...
ORGANISM(S): Homo Sapiens 
2026-04-17 | PXD077292 |
ProteomicsMolecular Glue Degraders of the RNA Binding Protein HuR to Treat BRAF-Mutant Colorectal Cancer
BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all colorectal cancer (CRC) patients, and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as Encorafenib are ineffective due to MAP kinase pathway reactivation driven by BRAF dimeriza...
ORGANISM(S): Homo Sapiens 
2025-12-21 | PXD072281 |
ProteomicsMolecular Glue Degraders of HuR to Treat BRAF-Mutant Colorectal Cancer
BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all colorectal cancer (CRC) patients, and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as Encorafenib are ineffective due to MAP kinase pathway reactivation driven by BRAF dimeriza...
ORGANISM(S): Homo Sapiens 
2026-04-19 | PXD077365 |
Sort   by:  
 Page size