Sort   by:  
 Page size 
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
TranscriptomicsInducible iPS Cells Support Full-term Development of Tetraploid Blastocyst–Complemented Embryos
Differentiated somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by forced expression of four transcription factors—Oct4, Sox2, Klf4, and c-Myc. However, it remains undetermined whether the reprogrammed iPS cells are fully pluripotent, resembling normal embryonic stem (ES...
ORGANISM(S): Mus musculus 
2010-08-18 | E-GEOD-17004 | biostudies-arrayexpress
TranscriptomicsCGH analyses for the Chinese indigenous pig breeds and commercial pig breeds [Agilent]
Since CNVs play a vital role in genomic studies, it is an imperative need to develop a comprehensive, more accurate and higher resolution porcine CNV map with practical significance in follow-up CNV functional analyses To detect CNV of pigs, we performed high density aCGH data of diverse pig breeds ...
ORGANISM(S): Sus scrofa 
2015-06-29 | E-GEOD-49299 | biostudies-arrayexpress
GenomicsLoss of EZH2 results in enhanced recruitment of EZH1, Pol II and Stat5 and precocious mammary gland development (SuperSeries)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-01-27 | E-GEOD-65285 | biostudies-arrayexpress
TranscriptomicsAkt-Induced Mitochondrial Dysfunction in the Heart
Sustained Akt activation induces cardiac hypertrophy (LVH), which may lead to heart failure. This study tested the hypothesis that Akt activation contributes to mitochondrial dysfunction in pathological LVH. Akt activation induced LVH and progressive repression of mitochondrial fatty acid oxidation ...
ORGANISM(S): Mus musculus 
2015-01-05 | E-GEOD-63848 | biostudies-arrayexpress
TranscriptomicsMicroRNA profile of tumorigenic cells during formation of pulmonary adenocarcinoma
Study designed to obtain microRNA profile of tumorigenic Sca-1+CD34+ cells during the formation of pulmonary adenocarcinoma. After intranasal infection with adenovirus CRE (Ad-Cre), lung adenocarcinoma was identified pathologically in Lox-stop-lox Kras (LSL-Kras) G12D mice. Sca-1+CD34+ cells were so...
ORGANISM(S): Mus musculus 
2014-08-02 | E-GEOD-60001 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rice collars were taken from wild type plants or antiOsLIC transgenic plants
30 collars were taken from wild type plants or antiOsLIC transgenic plants respectively. One collar from one plant only. The leaves are just sprout 2-3 cm (about 1-2 days) from the stem. For measuring the genes expression level, Wild type plants were taken as control. The developing collar from both...
ORGANISM(S): Oryza sativa 
2009-01-13 | E-GEOD-12097 | biostudies-arrayexpress
TranscriptomicsLoss of EZH2 results in precocious mammary gland development and the activation of STAT5-dependent genes
Establishment and differentiation of mammary alveoli during pregnancy are controlled by prolactin through the transcription factor STAT5. As pregnancy progresses mammary signature genes are activated in a defined temporal order, which coincides with the recruitment of STAT5 to respective regulatory ...
ORGANISM(S): Mus musculus 
2015-08-31 | E-GEOD-70440 | biostudies-arrayexpress
TranscriptomicsMPSS profiling of embryonic gonad and primordial germ cells
We used the MPSS technology to uncover gene expression profiling in a greater depth in the early embryonic gonads and primordial germ cells (PGCs) in the chicken. Total numbers of sequenced signatures were 1,012,533 and 995,676 for the PGCs and gonad. Using a false discovery rate cut-off of 0.05, we...
ORGANISM(S): Gallus gallus 
2007-02-28 | E-GEOD-5909 | biostudies-arrayexpress
TranscriptomicsThe gene expression profiling array of LncRNA between tumor tissues and paired non-tumor tissues in HBV-positive hapatocellular carcinoma
Investigation of whole genome gene expression level changes of LncRNAs in tumor tissues and paired non-tumor tissues in HBV-positive hapatocellular carcinoma. The different expression genes were further analysised. The human LncRNA microarray analysis of the 10 samples (5 non-tumor tissues and 5 pai...
ORGANISM(S): Homo sapiens 
2013-08-10 | E-GEOD-49713 | biostudies-arrayexpress
Sort   by:  
 Page size