Wang Li-Chong LC

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Unknown (48)
Metabolomics (9)
Genomics (3)
Proteomics (3)

Organisms

Homo sapiens (4)
Rattus norvegicus (1)
Mus musculus (1)

Repository

MetaboLights (9)
EGA (3)
pride (2)
iProX (1)

Tissue

Blood serum (1)
Heart (1)

Technology Type

Mass spectrometry (9)
Mass Spectrometry (2)
Shotgun proteomics (2)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (7)
Liquid Chromatography MS - positive - reverse phase (6)
Liquid Chromatography MS - negative (2)
Liquid Chromatography MS - positive (2)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - alternating - reverse phase (1)

Publication Date

2023 (4)
2022 (3)
2024 (2)
2020 (1)
2021 (1)
2025 (1)

CHEBI ID

CHEBI:30915 (4)
CHEBI:15887 (3)
CHEBI:15891 (3)
CHEBI:16196 (3)
CHEBI:16411 (3)
CHEBI:16450 (3)
CHEBI:16704 (3)
CHEBI:16865 (3)
CHEBI:17351 (3)
CHEBI:17596 (3)
CHEBI:18211 (3)
CHEBI:18237 (3)
CHEBI:18257 (3)
CHEBI:27897 (3)
CHEBI:28716 (3)
CHEBI:28875 (3)
CHEBI:30653 (3)
CHEBI:33508 (3)
CHEBI:136623 (2)
CHEBI:137228 (2)
CHEBI:13790 (2)
CHEBI:15611 (2)
CHEBI:15676 (2)
CHEBI:15727 (2)
CHEBI:15741 (2)
CHEBI:15746 (2)
CHEBI:15843 (2)
CHEBI:15882 (2)
CHEBI:15956 (2)
CHEBI:16040 (2)

Metabolite Name

Deoxyuridine (2)
Homoserine (2)
Hydrocinnamic acid (2)
Indole (2)
Indolelactic acid (2)
Inosine (2)
Kynurenic acid (2)
Oleic acid (2)
Ornithine (2)
Tryptophan (2)
(+/-)-2-Hydroxy-4-(methylthio)butanoic acid (1)
(1'S,2R,2'R,10'S,11'S,15'S)-17'-hydroxy-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane]-6',8'-diene-5,5'-dione (1)
(1-{1-[(4-hydroxy-3-methoxyphenyl)methyl]-7,8-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydro-2λ⁵-isoquinolin-2-yl}ethylidene)-λ⁴-oxidanyliumyl (1)
(10,14a-dihydroxy-2,2,4a,6a,6b,9,9,12a-octamethyl-docosahydropicen-13-yl)oxidanesulfonic acid (1)
(10S,14S)-10,14,20-trimethyl-16-methylidene-22-azahexacyclo[12.10.0.0²,¹¹.0⁵,¹⁰.0¹⁵,²³.0¹⁷,²²]tetracosan-5-ylium-7-olate (1)
(12aR)-4-(dimethylamino)-4a,5,10,12a-tetrahydroxy-6-methylidene-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aR)-7-chloro-4-(dimethylamino)-4,6,10,12a-tetrahydroxy-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aS)-4,7-bis(dimethylamino)-10,12,12a-trihydroxy-1,3,11-trioxo-9-(2-oxoacetamido)-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-2-carboximidic acid (1)
(12aS)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-5,10,12,12a-tetrahydroxy-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboximidic acid (1)
(13-{[5-(acetyloxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,6,6,11,15-pentamethyl-14-(6-methylhept-5-en-2-yl)-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-9-yl)oxidanesulfonic acid (1)
(13R)-5-(3,4-dihydroxyphenyl)-6,9,17,19,21-pentahydroxy-13-(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.0²,¹¹.0³,⁸.0¹⁵,²⁰]henicosa-2(11),3(8),5,9,15,17,19-heptaen-7-one (1)
(15Z)-Octadec-15-en-9,11,13-triynoic acid (1)
(1R)-1,4-bis({[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-3-hydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1R,16Z,24E,26E,28Z)-1,18,26,27-tetrahydroxy-19,30-dimethoxy-12-[1-(3-methoxy-4-oxocyclohexyl)propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,16Z,24E,26E,28Z)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-19,30-dimethoxy-15,17,21,23,29-pentamethyl-35-methylidene-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,2R,3R,11S,12S,14R,26R)-5,6',7',12-tetrahydroxy-6-methoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15(23),16(20),21-hexaen-22-yl acetate (1)
(1R,2S,3R,4R,5S,6R,7S)-1,3,4,5,7,8,9,10,10-Nonachlorotricyclo[5.2.1.0²,⁶]dec-8-ene (1)
(1R,6S,12R,15S)-5,5-Dimethyl-11,13-dioxatetracyclo[7.5.1.0¹,⁶.0¹²,¹⁵]pentadec-8-ene (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-hydroxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-methoxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-13-(hydroxymethyl)-23,25-dimethoxy-19,21,27-trimethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)

Release Date

2021 (12)
2025 (10)
2022 (6)
2024 (5)
2015 (3)
2023 (2)
2013 (2)
2026 (1)
2020 (1)
2019 (1)
2018 (1)
2017 (1)
2016 (1)
2011 (1)
2008 (1)

Lab affiliation

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing 100049, P. R. China (1)
State Key Laboratory of Reproductive Medicine and China International Joint Research Center on Environment and Human Health, Nanjing Medical University (1)

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Metabolomic fingerprinting of bull spermatozoa for identification of fertility signature metabolites

The objective of the study was to identify the fertility-associated metabolites in bovine spermatozoa using liquid chromatography-mass spectrometry (LC-MS). Six Holstein Friesian crossbred bulls (three high-fertile and three low-fertile bulls) were the experimental animals. Sperm proteins were isola...

2021-12-07 | MTBLS1071 | MetaboLights

Lung Lipidomic Alterations in Beagle Dogs Infected with Toxocara canis

Toxocariasis, mainly caused by Toxocara canis, and to a lesser extent, Toxocara cati, is a neglected parasitic zoonosis. The mechanisms that underlie the changes in lipid metabolism of T. canis infection in Beagle dogs' lungs remain unclear. Lipidomics is a rapidly emer...

2023-08-21 | MTBLS5583 | MetaboLights

Differential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells

Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...

2022-11-15 | MTBLS2352 | MetaboLights

Selective Regulation of Macrophage Lipid Metabolism via Nanomaterials’ Surface Chemistry

Understanding the interfacial structure between nanomaterials and lipoproteins is crucial for gaining profound insights into how nanomaterials impact lipoprotein structure and interfere with lipid metabolism. In this study, we employed graphene oxide (GO) nanosheets (NSs) with precisely controlled s...

ORGANISM(S): Homo sapiens (Human)

2025-05-06 | PXD044475 | Pride

Characterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse hearts

In mammals, the neonatal heart regenerates within a short time after birth, but adults lack this ability. We have shown that metabolic reprogramming is critical for cardiomyocyte proliferation in the neonatal heart. Herein, we revealed that cardiac metabolic reprogramming could be regulated by alter...

ORGANISM(S): Mus musculus (Mouse)

2024-07-02 | PXD039257 | Pride

Cell proliferation Metabolic reprogramming Postnatal heart regeneration Lactylation

Energy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights

Neuroactive metabolites and bile acids are altered in extremely premature infants with brain injury

The gut microbiome has been associated with pathological neurophysiological evolvement in extremely premature infants suffering from brain injury. The exact underlying mechanism and its associated metabolic signatures in infants are not fully understood. To decipher metab...

2023-12-30 | MTBLS7560 | MetaboLights

merged_dataset - samples

This dataset contains merged data from the 22 Hodgkin lymphoma and 5 reactive lymph node samples, including count data and cell cluster assignments.

EGAD00001006221 | EGA

ena-DATASET-BCCA-11-12-2019-18:47:10:446-1110 - samples

Single-cell gene expression was profiled for 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes (2 replicates were performed for RLN-1). Library preparation was performed with the 10x Chromium platform (3' version 2 assay). Sequencing was performed on an Illumina NextSeq. The BAM files were gener...

EGAD00001005739 | EGA

Single-cell RNA sequencing of 22 Hodgkin lymphoma tumors and 5 reactive lymph nodes

Hodgkin lymphoma (HL) is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of non-cancerous immune cells with rare malignant cells. Characterization of the cellular components and their spatial relationship is crucial to understanding crosstalk and the...

EGAS00001004085 | EGA

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