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ProteomicsCalcium-mediated calreticulin IRE1α interaction drives dynamic fluctuation of IRE1α activity under chronic endoplasmic reticulum stress
To investigate the mechanisms underlying fluctuating IRE1α phosphorylation under chronic endoplasmic reticulum stress, we performed co-immunoprecipitation coupled with mass spectrometry (IP-MS) to identify IRE1α-interacting proteins. Protein complexes were analyzed by LC-MS/MS, followed by bioinform...
ORGANISM(S): Homo Sapiens 
2026-01-30 | PXD073899 |
ProteomicsProteomic insights into the pathogenesis of intracerebral hemorrhage: The role of blend sign in hematoma expansion
The blend sign on CT imaging is a key predictor of hematoma growth in intracerebral hemorrhage (ICH), yet the underlying pathological mechanisms remain poorly understood. To address this, hematoma specimens from nine ICH patients with blend signs were collected via stereotactic minimally invasive pu...
ORGANISM(S): Homo Sapiens 
2025-08-21 | PXD067588 |
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