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UnknownCathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms.
Not available
S-EPMC6670178 | biostudies-literature
MetabolomicsDynamic change of IDO1 activity predicts survival in patients with unresectable stage III NSCLC and chemoradiotherapy

OBJECTIVES: High activity of Indoleamine 2,3-dioxygenase1 (IDO1) in lung cancer patients converts tryptophan (Trp), which is the essential amino acid for T cell metabolism, to kynurenine (Kyn) and consequently suppresses anti-tumor immune responses. We aimed to track the dynamics...

2022-08-05 | MTBLS5267 | MetaboLights
TranscriptomicsmiRNA profiling in HIV-1 latently infected cells
Herein expression trends of host miRNA were measured in HIV-1 latently infected and persistent replication cells, as well as the control cells. HIV-1 latency infection was established by infecting CEM-SS lymphocytes with HIV-1 Bru strain. After selection and long-term culture, the chronically infect...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-38388 | biostudies-arrayexpress
MetabolomicsPolicosanol Alleviates Chronic Stress-Induced Growth Impairment via Gut Microbiota-Metabolite Interactions: Insights from 16S rRNA Sequencing and LC-MS Metabolomics

Background/Objectives: Policosanol, a bioactive compound derived from rice bran wax, has demonstrated potential for alleviatingshown potential in combating stress, yet its underlying mechanisms remain elusive. This study aimed to elucidate its role in mitigating chronic stress-induced growth impa...

2025-10-21 | MTBLS13189 | MetaboLights
TranscriptomicsmRNA profiling in HIV-1 latently infected cells
Investigation of whole genome gene expression level changes in HIV-1 latented infected cells, compared to the replicated cells and control cells. In this study, the in vitro steady cell culture was used to explore the mRNA transcription signatures in HIV-1 infection. mRNA profiles were performed and...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-38634 | biostudies-arrayexpress
UnknownActinostephanus (Gesneriaceae), a new genus and species from Guangdong, South China.
Not available
S-EPMC9849016 | biostudies-literature
ProteomicsSexual Dimorphism in the Extracellular and Pericellular Matrix of Articular Cartilage
Male and female collagen-enriched fraction of cartilage from bovine knees. Full thickness cartilage plugs without subchondral bone were digested with chondroitinase for 24 hours to remove proteoglycans. Cartilage was further decellularized with SDS. LUM1_811145: channels 126, 127, 128 female, chan...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
MSV000092997 | MassIVE
TranscriptomicsQKI5-regulated miRNAs
microRNAs (miRNAs) accomplish a remarkable variety of biological functions. Their expression is tightly controlled, and the final production of a miRNA is dependent on the cooperation of multiple mechanisms and their net effect. Here we show that miR-124-1 is transcriptionally activated during eryth...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-57363 | biostudies-arrayexpress
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