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GenomicsMechanisms of Ikaros Tumor Suppression with HDAC1 through distinct histone markers in Pre-B ALL Leukemia
Ikaros functions as a master regulator of lymphocyte differentiation and a tumor suppressor. Ikaros binds DNA and regulates gene expression by chromatin remodeling. Mechanisms of Ikaros-mediated tumor suppression are unknown. Here we examined genome-wide occupancy of Ikaros and histone deacetylase 1...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44217 | biostudies-arrayexpress
UnknownMetabolic features of chronic fatigue syndrome.
Not available
S-EPMC5027464 | biostudies-literature
GenomicsH2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation
Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-34483 | biostudies-arrayexpress
UnknownSDU - software for high-throughput automated data collection at the Swiss Light Source.
Not available
S-EPMC10161886 | biostudies-literature
TranscriptomicsChromosome interaction copy number analysis of mouse neonatal liver cells, and undifferentiated and differentiated embryonic stem cells using circular chromosome conformation capture (4C) assays
Experimental design
• Using Circular chromosome conformation capture (4C) assay to uncovers epigenetically regulated intra- and inter-chromosomal interaction network
• To examine restrictions imposed by the nuclear structure on such cis/trans-chromosomal networks, we developed a high-through...
ORGANISM(S): Mus musculus 
2006-10-31 | E-MEXP-870 | biostudies-arrayexpress
UnknownProteomic analysis identifies key differences in the cardiac interactomes of dystrophin and micro-dystrophin.
Not available
S-EPMC8255133 | biostudies-literature
TranscriptomicsGene expression profiling in Nalm6 ALL leukemia cells
Identify the expression intensity for all genes in Nalm6 cells and all the genes are divided into 4 equal groups with group 1 containing the 25% of genes that were expressed at the highest levels, and group 4 containing the 25% of genes that were expressed at the lowest levels. Total RNA are isolate...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44214 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
UnknownInsights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta).
Not available
S-EPMC5547612 | biostudies-literature
Transcriptomicsgene profiling in silencing suppressor plants or in mirna mutants-Transcriptional and post-transcriptional changes in Arabidopsis plants that constitutively express suppressors of RNA silencing
gen107_ptgs - gene profiling in silencing suppressor plants or in mirna mutants - What are the genes that are differentially regulated in various tissues derived from silencing suppressor plants or miRNA mutants? - HcPro, P15, P19, CHS-RNAi (control), were grown on MS solid medium, and tissues were ...
ORGANISM(S): Arabidopsis thaliana 
2011-08-22 | E-GEOD-24693 | biostudies-arrayexpress
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