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TranscriptomicsTranscriptome Profile of CYC2 K.O. and WT during meiosis in Tetrahymena thermophila
Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks (DSBs) made by the Spo11 protein. The present study shed light on the functional role of Cyclin, CYC2, in Tetrahymena thermophila which has transcriptionally high expression le...
ORGANISM(S): Tetrahymena thermophila 
2016-04-06 | E-GEOD-79286 | biostudies-arrayexpress
ProteomicsCharacterization, Antioxidant Effects of Lycium ruthenicum Murr. Polysaccharides and its Protective Effects Against Oxaliplatin-Induced Peripheral Neurotoxicity by Inhibiting the RAS-RAF-MEK-ERK Signaling Pathway
Oxaliplatin is a frequently used chemotherapeutic agent; however, oxaliplatin-induced peripheral neuropathy (OIPN) is a prevalent adverse effect for which no effective treatment currently exists. Lycium ruthenicum Murr. (LR), a traditional Chinese medicinal herb also consumed as food, is rich in pol...
ORGANISM(S): Rattus Norvegicus 
2025-11-26 | PXD071288 |
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
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