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TranscriptomicsEffect of treatment OPM2 multiple myeloma cells with EPA, DHA or bortezomib
OPM2 cells were seeded in a 12-well plate at density of 10 × 103 cells/well and incubated with the indicated concentrations of compounds. OPM2 cells were treated with 50 µM of DHA/EPA (6 h) or 10 nM of bortezomib (4 h). Total RNA was extracted from cells using RNeasy Mini Kit (74104, Qiagen, Hilden,...
ORGANISM(S): Homo sapiens 
2022-06-26 | E-MTAB-11907 | biostudies-arrayexpress
ProteomicsMass spectrometry for the proteomics following RNA pull down of m6A methylated RN7SK in lung adenocarcinoma A549 cell line.
The aim of this project was to investigate the proteins that bind to m6A methylated RN7SK in lung adenocarcinoma A549 cell line. And mass spectrometry of A549 cell treated with or without m6A methylated RN7SK in three replicates.
ORGANISM(S): Homo Sapiens 
2022-04-12 | PXD033184 |
UnknownCarbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy.
Not available
S-EPMC10170720 | biostudies-literature
Proteomicsproteomics of m6A-High and m6A-Low LUAD tissues
The dataset includes the sequencing data of m6A-high and m6A-low LUAD tissues, each of which contains five biological replicates. A total of 3437 protein groups were obtained, 407 differential proteins were obtained . Exerllent repeatability for different biological replicates is indicated based on...
ORGANISM(S): Homo Sapiens 
2021-07-29 | PXD027633 |
MetabolomicsMitochondrial Transplantation Ameliorates Doxorubicin-Induced Cardiac Dysfunction via Activating Glutamine Metabolism
Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...
2025-03-13 | MTBLS7989 | MetaboLights
UnknownDiphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.
Not available
S-EPMC11053169 | biostudies-literature
UnknownCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Not available
S-SCDT-EMBOR-2021-53855-T | biostudies-other
ProteomicsProteomic identification of new diagnostic biomarkers of early-stage cutaneous mycosis fungoides
Primary cutaneous T-cell lymphoma (CTCL) is responsible for two-thirds of cutaneous lymphoma cases. Mycosis fungoides (MF), the most common subtype of CTCL comprises approximately 60% of CTCLs. Due to the similar clinical features of MF and inflammatory diseases such as eczema and psoriasis, early-s...
ORGANISM(S): Homo Sapiens 
2020-11-28 | PXD022798 |
ProteomicsIdentification of key factors in cartilage tissue during the progression of osteoarthritis using a non-targeted metabolomics strategy
This work used non-targeted metabolomics and screened out differential metabolites and metabolic pathways, providing a reliable theoretical basis for further study of specific markers and their specific pathways in the progression of OA.
ORGANISM(S): Homo Sapiens 
2023-04-02 | PXD041287 |
ProteomicsCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
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