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UnknownStatins as Potential Preventative Treatment of ETX and Multiple Pore-Forming Toxin-Induced Diseases.
Not available
S-EPMC10048941 | biostudies-literature
ProteomicsSMAX1/SMXL2 interacting proteins in Arabidopsis seedling through IP-MS
Karrikins (KARs) are a class of butenolide molecules found in smoke. KARs regulate many aspects of plant development and environmental responses, including Seed germination, hypocotyl elongation, leaf shape, root development, and resistance to drought, salt, and heat stress. The transcriptional repr...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-06-22 | PXD052400 | Pride
Smax1 Arabidopsis thaliana Ip-ms Smxl2 Seedling Karrikin 
TranscriptomicsExpression data from human hepatic stellate cell line LX2 treated with suberoylanilide hydroxamic acid (SAHA) or valproic acid (VPA)
Suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) are both histone deacetylases inhibitor (HDACi), and are able to attenuate the activation of hepatic stelllate cells. To explore the underlying molecular mechanisms, we performed gene expression profile analyses of human hepatic stellate...
ORGANISM(S): Homo sapiens 
2016-04-07 | E-MTAB-3764 | biostudies-arrayexpress
ProteomicsProteomic analysis of tumor tissues form high-grade serous ovarian cancer patients
In the present project, in order to explore the molecular basis of platinum resistance and further determine potential biomarkers and therapeutic targets for high-grade serous ovarian cancer (HGSOC), we conducted a comparative proteomic analysis to identify the differentially expressed proteins betw...
ORGANISM(S): Homo Sapiens 
2021-09-30 | PXD028225 |
ProteomicsWarburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis
Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis
ORGANISM(S): Homo Sapiens 
2023-07-10 | PXD043632 |
ProteomicsThe Proteome of Shiraia bambusicola Conidia under Different Light Conditions
This project investigates the molecular mechanisms by which blue light enhances conidiation in the medicinal fungus Shiraia bambusicola. We found that blue light not only advanced conidia production by 6 days but also increased the yield by over 7-fold. Through a comprehensive proteomic analysis, we...
ORGANISM(S): Shiraia Bambusicola 
2026-08-12 | PXD070936 |
MetabolomicsHost specific sphingomyelin is critical for replication of diverse RNA viruses
Lipids and lipid metabolism play an important role in RNA virus replication, which typically occurs on host cell endomembrane structures in the cytoplasm through mechanisms that are not yet fully identified. We conducted genome-scale CRISPR screening and identified sphingomyelin synthase 1 (SMS1; en...
2026-10-29 | MTBLS11308 | MetaboLights
ProteomicsPhosphoproteomics attributes aberrant signaling events to a druggable kinome in hepatocellular carcinom
To connect aberrant phospho-signaling events to therapeutic vulnerabilities in hepatocellular carcinoma (HCC), we performed a mass-spectrometry-based phosphoproteomic quantification of human HCC tumors, adjacent tissues and cell lines. We developed an integrated pipeline as the inference of druggabl...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD023840 |
UnknownMapping genomic loci implicates genes and synaptic biology in schizophrenia.
Not available
S-EPMC9392466 | biostudies-literature
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