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ProteomicsSystemic application of IL-4 attenuates secondary local inflammation processes and enhances functional recovery after traumatic spinal cord injury in rats.
Background: Traumatic spinal cord injury (SCI) triggers local and systemic inflammation cascades, limiting neuroregeneration and impeding functional recovery. We investigated the systemic effect of immunomodulation with Interleukin-4 (IL-4) on the local immune reaction and regeneration in injured sp...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-03-16 | PXD065980 | Pride
Immunomodulation Catwalk xt gait analysis Seromics Spinal cord injury Il-4 
Transcriptomicsm6A-dependent regulation of messenger RNA stability
N6-methyladenosine (m6A) is the most prevalent internal modification present in the mRNA of all higher eukaryotes. Here we present that m6A is selectively recognized by human YTH domain family (YTHDF2) protein to regulate mRNA degradation. By using crosslinking and immunoprecipitation, we have ident...
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-49339 | biostudies-arrayexpress
GenomicsINO80 complex in the core regulatory network governing ESC self-renewal [ChIP-Seq]
Embryonic stem cell (ESC) self-renewal and pluripotency is controlled by the coordinated action of transcription factors and chromatin regulators. Compared to the pluripotency transcription factors, the function of the chromatin regulators, especially the ATP-dependent chromatin remodelers, remains ...
ORGANISM(S): Mus musculus 
2014-05-16 | E-GEOD-49137 | biostudies-arrayexpress
UnknownRehmannia glutinosa extract activates endothelial progenitor cells in a rat model of myocardial infarction through a SDF-1 α/CXCR4 cascade.
Not available
S-EPMC3548813 | biostudies-literature
TranscriptomicsINO80 complex in the core regulatory network governing ESC self-renewal
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-05-16 | E-GEOD-49252 | biostudies-arrayexpress
ProteomicsCapillary Zone Electrophoresis-Electron-Capture Collision-Induced Dissociation on a Quadrupole Time-of-Flight Mass Spectrometer for Top-Down Characterization of Intact Proteins
Mass spectrometry (MS)-based denaturing top-down proteomics (dTDP) requires high-capacity separation and extensive gas-phase fragmentation of proteoforms. Herein, we coupled capillary zone electrophoresis (CZE) to electron-capture collision-induced dissociation (ECciD) on an Agilent 6545 XT quadrupo...
ORGANISM(S): Bos taurus (Bovine) Equus caballus (Horse) 
2023-01-05 | PXD030373 | Pride
Electron-capture collision-induced dissociation Top-down Capillary zone electrophoresis 
TranscriptomicsGene expression profiles in testis of pigs with extreme high and low levels of androstenone.
Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarrays to study the expression of thousands of genes simultaneously in testis of high and low a...
ORGANISM(S): Sus scrofa 
2007-11-26 | E-GEOD-7409 | biostudies-arrayexpress
UnknownCapillary Zone Electrophoresis-Electron-Capture Collision-Induced Dissociation on a Quadrupole Time-of-Flight Mass Spectrometer for Top-Down Characterization of Intact Proteins.
Not available
S-EPMC8576897 | biostudies-literature
UnknownClinical and Molecular Characterization of Patients with Fructose 1,6-Bisphosphatase Deficiency.
Not available
S-EPMC5412439 | biostudies-literature
UnknownMultiplexed Nanoparticle Protein Corona Enables Accurate and Precise Deep Plasma Proteomics.
Not available
S-EPMC12604036 | biostudies-literature
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