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Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
In this study Guo et al. revealed an endocrine pathway regulated by skeletal muscle IRF4 that manipulates liver pathology. Mice with skeletal muscle specific ablation of IRF4 show ameliorated liver steatosis, inflammation, and fibrosis, without changes in body weight on nonalcoholic steatohepatitis ...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-13 | PXD045324 | Pride
The coiled-coil domain of EPG5 was synthesized as follows: Biotin-MNKNEAVSQQIHVLQKEVRQLQAE AAQ (from Beijing SciLight Biotechnology, LCC). 1 mg of this short peptide was incubated with ES cells lysates followed by immunoprecipitation with anti-biotin beads. The precipitates were extensively washed w...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-25 | PXD012563 | Pride
abundance based on sequence+intensity from multiple files, Interaction consistency score: 11.4, Coverage: 77
ORGANISM(S): 4565 
2019-00-00 | 3803621201 | PAXDB
This data set contains the raw data of proteinomic analysis of dorsal root ganglions (DRGs) in WT and MLKL-KO mice under basal condition and after CFA treatment, and MLKL-based IP-MS analysis of WT DRGs under basal condition and after CFA treatment.
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077273 |
Proteomics of human gastric tissues derived from chronic non-atrophic gastritis (CNAG) and gastric intestinal metaplasia (GIM)
ORGANISM(S): Homo Sapiens 
2025-11-25 | PXD071234 |
To understand Hashimoto's Thyroiditis and translate this knowledge to clinical applications, we took mass spectrometric analysis on thyroid tissue fine-needle puncture from HT patients and healthy people in an attempt to make a further understanding of the pathogenesis of Hashimoto's Thyroiditis.
ORGANISM(S): Homo Sapiens 
2021-09-10 | PXD028448 |
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