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TranscriptomicsSmall RNAs in Chlamydomonas reinhardtii
RNA populations in Chlamydomonas reinhardtii Keywords: Highly parallel pyrosequencing Small RNAs were prepared from Chlamydomonas reinhardtii total extracts,ligated to a 3' adaptor and a 5' acceptor sequentially, and then RT-PCR amplified. PCR products were reamplified using a pair of 454 cloning pr...
ORGANISM(S): Chlamydomonas reinhardtii 
2007-05-15 | E-GEOD-7308 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse ES and iPS cells
Induced pluripotent stem (iPS) cells were produced from reprogramming of somatic cells, and they are shown to possess pluripotent properties similar to embryonic stem (ES) cells. Here we used microarrays to detail the global expression pattern among the ES cells and iPS cells, as well as the origina...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21515 | biostudies-arrayexpress
TranscriptomicsThe response and recovery of Arabidopsis thaliana transcriptome to phosphate starvation [At35b_MR]
Background: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant ...
ORGANISM(S): Arabidopsis thaliana 
2012-06-17 | E-GEOD-33996 | biostudies-arrayexpress
TranscriptomicsThe response and recovery of Arabidopsis thaliana transcriptome to phosphate starvation [ATH1-121501]
Background: Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant ...
ORGANISM(S): Arabidopsis thaliana 
2012-06-17 | E-GEOD-33790 | biostudies-arrayexpress
TranscriptomicsSmall RNAs serve as a genetic buffer against genomic shock in Arabidopsis interspecific hybrids and allopolyploids
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are produced in diverse species and control gene expression and epigenetic regulation. Although physiological and developmental roles of miRNAs and siRNAs have been extensively studied in plants and animals, expression diversity and evolution of...
ORGANISM(S): Arabidopsis arenosa 
2009-07-30 | E-GEOD-15443 | biostudies-arrayexpress
TranscriptomicsCharacterization of AGO1-/AGO4-associated smRNAs
To fully characterize smRNAs associated with AGO1 and AGO4, we developed a two-step protocol to purify AGO/smRNA complexes from flowers, leaves, roots and seedlings with enhanced purity, and sequenced the smRNAs by IlluminaM-CM-"M-BM-^@M-BM-^Ys technology. We identified some additional miRNAs, colla...
ORGANISM(S): Arabidopsis thaliana 
2011-04-19 | E-GEOD-28591 | biostudies-arrayexpress
Transcriptomicsm6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency
N6-methyladenosine (m6A) has been recently identified as a conserved epitranscriptomic modification of eukaryotic mRNAs, but its features, regulatory mechanisms, and functions in cell reprogramming are largely unknown. Here, we report m6A modification profiles in the mRNA transcriptomes of four cell...
ORGANISM(S): Mus musculus 
2015-03-10 | E-GEOD-52125 | biostudies-arrayexpress
TranscriptomicsDCL4-Dependent Clusters of PhasiRNAs in Rice.
The osdcl4-1 mutant exhibits much severer developmental defects than dcl4 in Arabidopsis, suggesting that Os DCL4 may process broader substrates in rice. By deep sequencing of small RNAs from different tissues of wild types and osdcl4-1, we revealed that 21-nucleotide siRNAs were largely dependent o...
ORGANISM(S): Oryza sativa 
2012-03-29 | E-GEOD-22763 | biostudies-arrayexpress
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
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