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ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD068797 | Pride
Invasive fungal infections Protein-rna interaction covalent inhibitors Fumaramidmycin derivatives Ribosome assembly factor mrt4 Antifungal target identification 
ProteomicsInhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an unexploited antifungal strategy-qualitative proteomic
The rise of drug resistance and limitations of current antifungal treatments highlight the urgent need for innovative antifungal strategies. Here we present the development of cis-fumaramidmycin-derived analogues as a novel chemotype inhibiting the interactions of ribosome assembly factor Mrt4 with ...
ORGANISM(S): Candida albicans (Yeast) 
2026-04-27 | PXD073550 | Pride
Ribosome assembly factor Azole-resistant fungi Protein-rna interaction Fumaramidmycin-based derivatives Target identification 
ProteomicsPan-Cancer Proteogenomic Characterization of Metastatic Brain Tumors
4D-DIA data Derived from Paired Primary Tumors, Brain Metastasis and Giloblastoma
ORGANISM(S): Homo Sapiens 
2025-01-20 | PXD059751 |
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