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ModelsQi2013 - IL-6 and IFN crosstalk model
Qi2013 - IL-6 and IFN crosstalk model This model [BIOMD0000000544] describes the crosstalk between IFN-gamma and IL-6 induced signalling; it aims to outline mechanisms and factors that may control the interaction between both signalling pathways, discussing a role of heterodimer formation in signa...
2024-09-02 | BIOMD0000000544 | BioModels
ModelsQi2013 - IL-6 and IFN crosstalk model (non-competitive)
Qi2013 - IL-6 and IFN crosstalk model (non-competitive) This model [BIOMD0000000543] describes the crosstalk between IFN-gamma and IL-6 induced signalling; it aims to outline mechanisms and factors that may control the interaction between both signalling pathways, discussing a role of heterodimer f...
2024-09-02 | BIOMD0000000543 | BioModels
GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
ProteomicsNeutralization mechanism of a HipA-like toxin targeting isoleucyl-tRNA synthetase
HipAB is a type II toxin-antitoxin (TA) system that targets and inactivates specific aminoacyl-tRNA synthetases in response to various stresses. While the molecular targets and neutralization mechanisms of several HipAB-like TA systems have been well characterized, their structural and functional di...
ORGANISM(S): Escherichia Coli K-12 
2025-04-11 | PXD062828 |
ProteomicsInsulin Signaling Regulates Longevity Through Protein Phosphorylation in Caenorhabditis elegans
Insulin/IGF-1 Signaling (IIS) is known to constrain longevity by inhibiting the transcription factor FOXO. How phosphorylation mediated by IIS kinases regulates lifespan beyond FOXO remains unclear. Here, we profile IIS-dependent phosphorylation changes in a large-scale quantitative phosphoproteomic...
ORGANISM(S): Caenorhabditis Elegans 
2021-06-10 | PXD020440 |
UnknownA common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.
Not available
S-EPMC4605818 | biostudies-literature
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