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MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid β-...

2022-05-31 | MTBLS4709 | MetaboLights
UnknownRandomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Not available
S-EPMC5569675 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of human pancreatic endocrine cells from Juvenile, adult control and type 2 diabetic donors.
We successfully sequenced and annotated more than 400 cells from child, adult control, type 1 diabetes and type 2 diabetes donors. We detect donor-type specific transcript variation. We also report that cells from child donors have less defined gene signature. Cells from type 2 diabetes donors resem...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-83139 | biostudies-arrayexpress
UnknownSWR1 complex poises heterochromatin boundaries for antisilencing activity propagation.
Not available
S-EPMC2863710 | biostudies-literature
UnknownCholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.
Not available
S-EPMC5518634 | biostudies-literature
UnknownLoganetin protects against rhabdomyolysis-induced acute kidney injury by modulating the toll-like receptor 4 signalling pathway.
Not available
S-EPMC6451112 | biostudies-literature
UnknownNovel amdoparvovirus infecting farmed raccoon dogs and arctic foxes.
Not available
S-EPMC4257837 | biostudies-literature
UnknownFusion membrane proteins derived subunit vaccine candidates effectively protect against Mycoplasma bovis challenge in mice.
Not available
S-EPMC12492813 | biostudies-literature
UnknownEdible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion.
Not available
S-EPMC10469825 | biostudies-literature
UnknownTherapeutic potential of gene therapy for gastrointestinal diseases: Advancements and future perspectives.
Not available
S-EPMC10471515 | biostudies-literature
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