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ProteomicsInteraction of Arabidopsis Cryptochrome 2 with PRR9 transmits blue light intensity fluctuation to circadian clock
Circadian pace is modulated by light intensity, known as the Aschoff’s rule, with largely unrevealed mechanisms. Here we report that photoreceptor CRY2 mediates blue light input to circadian clock by directly interacting with clock core component PRR9 in blue light dependent manner. This physical in...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-10-06 | PXD035252 | Pride
Aschoff’s rule  circadian clock  light intensity  cry2  prr9 
MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
UnknownDistinct body-size responses to warming climate in three rodent species.
Not available
S-EPMC9006008 | biostudies-literature
TranscriptomicsGenome-wide analysis of gene expression in MLL translocation transformed mouse leukemia cell lines
The purpose of this study is to investigate the transcriptional programs as it relates to disease latency initiated by different MLL fusion proteins, including: MLL-AF1p, MLL-AF6, MLL-Gas7, MLL-AF9 and MLL-ENL. Leukemia cell lines were established by transforming kit+ mouse bone marrow cells with re...
ORGANISM(S): Mus musculus 
2016-07-07 | E-GEOD-73457 | biostudies-arrayexpress
UnknownUntangling impacts of global warming and Interdecadal Pacific Oscillation on long-term variability of North Pacific tropical cyclone track density.
Not available
S-EPMC7546700 | biostudies-literature
ProteomicsFunctional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Accurate chromosome segregation is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), to inhibit the anaphase-promoting complex or cyclosome (APC/C). Cdc20 is an essential mitotic regulator since it promotes mitotic exit through activating...
ORGANISM(S): Homo sapiens (Human) 
2023-12-06 | PXD045411 | Pride
Cdc20 cry box crispr cas9 mitosis 
UnknownLapsed El Nino impact on Atlantic and Northwest Pacific tropical cyclone activity in 2023.
Not available
S-EPMC11306224 | biostudies-literature
ProteomicsSelf-priming of Plk1 binding to BubR1 ensures accurate mitotic progression
Plk1 is a key mitotic kinase that localizes to distinct subcellular structures to promote accurate mitotic progression. Plk1 recruitment depends on direct interaction between polo-box domain (PBD) on Plk1 and PBD binding motif (PBD BM) on the interactors. However, recent study showed that PBD BM alo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096264 | MassIVE
ProteomicsUrinary protein changes during the short-term growth and development of rats
Can the urine proteome reflect short-term changes in the growth and development of animals? Do short-term developmental effects on urinary protein need to be considered when performing urine marker studies using model animals with faster growing periods? In this study, urine samples were collected f...
ORGANISM(S): Rattus Norvegicus 
2023-06-07 | PXD042780 |
ProteomicsChanges in the urinary proteome of rats after short-term intake of minerals
Magnesium is an important mineral in living organisms and has multiple functions in the human body, wherein it plays an important therapeutic and preventive role in a variety of diseases. In the present study, urine samples of rats before and after gavage of magnesium threonate were collected, and t...
ORGANISM(S): Rattus Norvegicus 
2023-10-13 | PXD046121 |
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