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ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
ProteomicsIntegrated Multi-Omics Reveal Polycomb Repressive Complex 2 Restricts Human Trophoblast Induction
Human naive pluripotent stem cells have unrestricted lineage potential. Underpinning this property, naive cells are thought to lack chromatin-based lineage barriers. However, this assumption has not been tested. Here, we define the chromatin-associated proteome, histone post-translational modificati...
ORGANISM(S): Homo sapiens (Human) 
2022-05-09 | PXD032792 | Pride
H3k27me3 Trophoblast fate Polycomb repressive complex 2 (prc2) Chromatin proteomes Human pluripotent stem cells 
ProteomicsHistione HCD and CID datasets for evaluation of search engines
To identify confident spectra from histone peptides containing PTMs, we present a method in which one kind of modification is searched each time. We then combine the identifications of multiple search engines to obtain confident results. We find that two search engines, pFind and Mascot, identify mo...
ORGANISM(S): Homo sapiens (Human) 
2014-09-01 | PXD001118 | Pride
Proteomics Search engine Post-translational modification Data analysis Histone 
ProteomicsA novel quantitative mass spectrometry platform for determining site-specific protein O-GlcNAcylation dynamics
Over the past decades, protein O-GlcNAcylation has been found to play a fundamental role in cell cycle control, metabolism, transcriptional regulation, and cellular signaling. Nevertheless, quantitative approaches to determine in vivo GlcNAc dynamics at a large-scale are still not readily available....
ORGANISM(S): Homo sapiens (Human) 
2016-07-19 | PXD002591 | Pride
Mass spectrometry method determines protein o-glcnacylation rates 
UnknownHost sex-specific parasites in a functionally dioecious fig: a preference way of adaptation to their hosts.
Not available
S-EPMC3790544 | biostudies-literature
UnknownE3 ubiquitin ligase TRIM2 identified as a novel suppressor of CYP11B2 and aldosterone production.
Not available
S-EPMC11671668 | biostudies-literature
UnknownEFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway.
Not available
S-EPMC4546460 | biostudies-literature
UnknownA Conserved Planthopper MATH-BTB Protein Regulates Fecundity in <i>Nilaparvata legens</i> Stal.
Not available
S-EPMC12785250 | biostudies-literature
UnknownGibberellin Induced Transcriptome Profiles Reveal Gene Regulation of Loquat Flowering.
Not available
S-EPMC8460860 | biostudies-literature
UnknownCell type-resolved proteomics reveals intra- and intercellular signaling in Alzheimer's disease.
Not available
S-EPMC12889647 | biostudies-literature
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