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ProteomicsAn impaired respiratory electron chain triggers down-regulation of the energy metabolism and de-ubiquitination of solute carrier amino acid transporters
We integrated metabolome and proteome profiles of the parental cell line 143B.TK- versus ?0, including PTM analyses such as phosphorylation and ubiquitination to characterize the impact of the absence of mtDNA for the entire cell. For quantitative proteome profiling, we used a shotgun LC-MS/MS appro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080873 | MassIVE
ProteomicsImproving identification of lysine acetylated peptides using molecularly imprinted monolith prepared by a deep eutectic solvents monomer
A novel approach based on molecularly imprinted polymer (MIP) was developed to improve the extraction capacity of lysine acetylation peptide in real sample. Green deep eutectic solvents (DESs) were introduced and used as one of synergistic functional monomers with zinc acrylate (ZnA). Glycine-glycin...
ORGANISM(S): Mus Musculus 
2021-10-08 | PXD029000 |
ProteomicsStellettin B renders glioblastoma vulnerable to poly (ADP-ribose) polymerase inhibitors via suppressing homology-directed repair
Glioblastoma (GBM) is the most malignant tumor of the central nervous system. Current first-line post-surgery regimens for GBM including radiotherapy and temozolomide (TMZ) chemotherapy show very limited efficacy, with a median overall survival of only 15 months. Therefore, the development of therap...
ORGANISM(S): Homo Sapiens 
2022-10-11 | PXD037301 |
UnknownSmall-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Not available
S-EPMC6812656 | biostudies-literature
UnknownProgression of Gastrointestinal Injury During Antiplatelet Therapy After Percutaneous Coronary Intervention: A Secondary Analysis of the OPT-PEACE Randomized Clinical Trial.
Not available
S-EPMC10656648 | biostudies-literature
UnknownExpert Consensus on Pathological Diagnosis of Intrahepatic Cholangiocarcinoma (2022 version).
Not available
S-EPMC10752808 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownVariation in global trauma care: a survey of 187 hospitals across 51 countries.
Not available
S-EPMC12598983 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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