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Plasticity of differentiated cells has been proved by nuclear transfer, induced pluripotent cells and transdifferentiation. Here we show that by transduction of 3 factors (FOXA3, HNF1A and HNF4A), human fetal fibroblasts can be converted to hepatocyte-like cells (hiHep cells), expressing hepatic mar...
ORGANISM(S): Homo sapiens 
It has been demonstrated that vitamin C enhances reprogramming efficiency during inducing pluripotent stem cells, however, the underlying mechanisms are not fully understood. To find the downstream target genes of vitamin C and investigate the mechanism of vitamin C on reprogramming promotion, we pe...
ORGANISM(S): Mus musculus 
Differential Proteomic Analysis on Propsilocerus akamusi(Tokunaga) Under the Stress of Cadmium using iTRAQ labeling technique
ORGANISM(S): Propsilocerus Akamusi 
2018-02-06 | PXD008880 |
The objectives of this study were to investigate response and tolerance of Macleaya cordata to lead(Pb)toxicity based on comparative analysis of proteome.
ORGANISM(S): Macleaya Cordata 
2022-11-14 | PXD038143 |
The flower chambers of sacred lotus (Nelumbo nucifera) can maintain a relatively stable temperature during anthesis despite the large environmental temperature fluctuations. However, the regulatory mechanism of floral thermogenesis remains largely unclear. To further understand the molecular basis o...
ORGANISM(S): Nelumbo Nucifera 
2021-02-20 | PXD024269 |
By conducting TMT labeled quantitative proteomic analysis on the leaves of Radix Isatidis under different stress conditions, the potential biological mechanisms of the impact of abiotic stress on the quality of Radix Isatidis were studied.
ORGANISM(S): Isatis Tinctoria 
2024-11-25 | PXD058215 |
The programmed cell death protein 1 (PD-1) / programmed death-ligand 1 (PD-L1) axis represents a cornerstone of cancer immunotherapy, yet the dynamic shuttling of PD-L1 between endosomal recycling and lysosomal degradation routes limits durable responses. Using a CRISPR screen targeting glycosphingo...
ORGANISM(S): Homo Sapiens 
2026-02-27 | PXD075012 |
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