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MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
UnknownAging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages.
Not available
S-EPMC7431827 | biostudies-literature
TranscriptomicsAlterations in the gene expression profile in SKOV3 cells exposed to elaiophylin
Elaiophylin was screened and identified as a novel autophagy inhibitor, with significant antitumor efficacy as a single agent. To explore the mechanisms by which elaiophylin kills cancer cells, NimbleGen 12x135K microarrays were used to find the gene expression changes in SKOV3 cells treated with el...
ORGANISM(S): Homo sapiens 
2022-06-07 | GSE205529 | GEO
UnknownSeven New Species of Anastatus Motschulsky (Hymenoptera: Chalcidoidea: Eupelmidae) from China Identified Based on Morphological and Molecular Data.
Not available
S-EPMC11594841 | biostudies-literature
ProteomicsEvaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis
The pathophysiology of Alzheimer’s disease (AD) is multifactorial with characteristic extracellular accumulation of amyloid-beta (Aβ) and intraneuronal aggregation of hyperphosphorylated tau in the brain. Development of disease-modifying treatment for AD has been challenging. Recent studies suggest ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039514 | Pride
Amyloid beta Alzheimer’s disease Pink1. Tetramethylpyrazine nitrone Proteomic analysis 
MetabolomicsSymbiotic bacteria-derived organic acids protect Delia antiqua larvae from entomopathogenic fungal infection

The protection of associated microbiota for their animal hosts against pathogen infection has been studied widely over the last 100 years. However, how those microbes protect the animal host is limitedly investigated. In former studies, body surface microbes of one insect, Delia antiqua,...

2020-11-12 | MTBLS2074 | MetaboLights
UnknownComparative Transcriptome Analysis of Sexual Differentiation in Male and Female Gonads of Nao-Zhou Stock Large Yellow Croaker (Larimichthys crocea).
Not available
S-EPMC11591422 | biostudies-literature
UnknownMolecular characterization of the microRNA-138-Fos-like antigen 1 (FOSL1) regulatory module in squamous cell carcinoma.
Not available
S-EPMC3220531 | biostudies-literature
UnknownLong-term exercise prevents hepatic steatosis: a novel role of FABP1 in regulation of autophagy-lysosomal machinery.
Not available
S-EPMC6902714 | biostudies-literature
UnknownChildhood trauma and cognitive deficits in patients with schizophrenia: mediation by orbitofrontal cortex H-shaped sulci volume.
Not available
S-EPMC9177195 | biostudies-literature
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