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TranscriptomicsThe Role of the E2F1 transcription factor in the innate immune response to systemic LPS [mRNA]
Our recent study of gene expression in mice treated with LPS systemically identified the E2F1 transcription factor as a novel regulator of innate immune response in lung, liver, and spleen tissue. Our follow up studies showed that RNAi-mediated inhibition or E2F1 gene deficiency lead to reduced infl...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-33901 | biostudies-arrayexpress
TranscriptomicsThe Role of the E2F1 transcription factor in the innate immune response to systemic LPS [miRNA]
Our recent study of gene expression in mice treated with LPS systemically identified the E2F1 transcription factor as a novel regulator of innate immune response in lung, liver, and spleen tissue. Our follow up studies showed that RNAi-mediated inhibition or E2F1 gene deficiency lead to reduced infl...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-33900 | biostudies-arrayexpress
TranscriptomicsPulmonary innate immune response to ozone and TLR2 agonist Pam3CYS in C57BL/6 mice
Rationale: Previous work demonstrated that pre-exposure to ozone primes innate immunity and increases TLR4-mediated response to subsequent stimulation with lipopolysaccharide (LPS). To further explore the pulmonary innate immune response to ozone exposure, we investigated the effect of ozone in com...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-38014 | biostudies-arrayexpress
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