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ProteomicsTranslatome and Translation Machinery Remodeling by eIF4A Inhibitors Mediates Antitumor Potency.
Protein synthesis-targeting agents against eIF4A activity, including rocaglates, are actively pursued as anticancer and antiviral therapies. Yet, their full effect on the translational landscape is unknown, especially with regards to up-regulated proteins and drug-activated translation factors that ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-23 | PXD022556 | Pride
Cancer Eiffa Matrix Translatome Rocaglate Pulse silac Translate 
ProteomicsCervicovaginal dysbiosis is associated with significant changes in the cervicovaginal proteome related to immune activation and increased cell death
Cervicovaginal microbiome dysbiosis is associated with increased prevalence and incidence of sexually transmitted infections including HIV. We compared the cervicovaginal proteome as characterised by mass-spectrometry of four groups of African female sex workers (total N=50) grouped by microbiome co...
ORGANISM(S): Homo sapiens (Human) 
2015-09-25 | PXD001435 | Pride
Bacterial vaginosis/ cervicovaginal microbiome/ cervicovaginal proteome/ hiv/ lactobacillus crispatus/ mass spectrometry 
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