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ProteomicsProtein kinase A phosphorylation of perilipin 5 on serine 155 regulates liver lipolysis via interactions with adipose triglyceride lipase
Perilipin (PLIN) 5 is a lipid droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). We detected phosphorylation on S155, S161 and S163 of recombinant PLIN5 ...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-11 | PXD021969 | Pride
Lipid droplets Fatty acid Perilipin Lipase Triglycerides Lipid metabolism Phosphorylation 
ProteomicsProteome analysis of human visceral and subcutaneous adipocytes identifies altered metabolic control points
Adipose tissue is a primary regulator of energy balance and metabolism. The distribution of adipose tissue depots is of clinical interest because the accumulation of upper-body subcutaneous (ASAT) and visceral adipose tissue (VAT) is associated with cardiometabolic diseases, whereas lower-body glute...
ORGANISM(S): Homo sapiens (Human) 
2021-04-19 | PXD018314 | Pride
Lipid metabolism Proteomics Swathßms Adipose tissue Obesity 
UnknownGWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.
Not available
S-EPMC9385867 | biostudies-literature
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