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ProteomicsUnderstanding the physiological role of asparaginyl endopeptidase (AEP)/Legumain
Understanding the regulation of lysosomal proteolytic/hidrolytic capacity has been recently advanced in a huge manner by the discovery of the lysosome-mTOR-TFEB pathway connecting nutrient sensing, autophagy and de novo lysosome generation. But, how lysosomes can adjust their proteolytic/hidrolytic ...
ORGANISM(S): Homo sapiens (Human) 
2019-01-09 | PXD011473 | Pride
Mvo26630 Wt mefs Time course Nanolc-ms/ms 
TranscriptomicsGBM cell lines derived and propagated according to Cambridge protocol
We screened the gene expression in GBM cell lines cultured under serum-free conditions. We have special interest in genes associated with glial development such as NG2, Olig2 and PDGFRa. This microarray data gave us an idea about the expression of these genes and made the basis for further investiga...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-15846 | biostudies-arrayexpress
TranscriptomicsProfiling by array of human Glioblastoma multiforme (GBM) tumor samples to asses the intra-tumoral heterogeneity in genomic copy number aberrations
Glioblastoma multiforme (GBM) is a highly heterogeneous disease that shows an wide range of genetic abnormalities in comparison to other astrocytic tumors. We have extracted between 4 and 8 tumor subsamples from different areas of the malignant tissue that were at least 1cm apart. Our aim to asses t...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-MTAB-1215 | biostudies-arrayexpress
TranscriptomicsExpression profiling of glioblastoma neural stem cells and reprogrammed derivatives
Glioblastoma-derived neural stem (GNS) cells were reprogrammed to induced pluripotent stem (iPS) cells by transgenic expression of OCT4 and KLF4. Gene expression profiling was performed in comparison to normal neural stem (NS) cells reprogrammed in parallel, as well as standard ES cells as an indepe...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-MTAB-1273 | biostudies-arrayexpress
TranscriptomicsHigh-resolution methylation profiling of glioblastoma neural stem cells and reprogrammed derivatives
Glioblastoma-derived neural stem (GNS) cells were reprogrammed to induced pluripotent stem (iPS) cells by transgenic expression of OCT4 and KLF4. Genome-wide DNA methylation status was profiled at 485,000 loci to assess epigenetic erasure and restoration due to reprogramming and redifferentiation to...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-MTAB-1271 | biostudies-arrayexpress
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
TranscriptomicsMethylation profiling of glioblastoma neural stem cells and reprogrammed derivatives
Glioblastoma-derived neural stem (GNS) cells were reprogrammed to induced pluripotent stem (iPS) cells by transgenic expression of OCT4 and KLF4. Genome-wide DNA methylation status was profiled at 27,578 CpG sites to assess epigenetic erasure and restoration due to reprogramming and redifferentiatio...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-MTAB-1275 | biostudies-arrayexpress
TranscriptomicsHigh-resolution methylation profiling of glioblastoma neural stem cells and reprogrammed derivatives
Glioblastoma-derived neural stem (GNS) cells were reprogrammed to induced pluripotent stem (iPS) cells by transgenic expression of OCT4 and KLF4. Genome-wide DNA methylation status was profiled at 485,000 loci to assess epigenetic erasure and restoration due to reprogramming and redifferentiation to...
ORGANISM(S): Homo sapiens 
2013-03-15 | E-MTAB-1274 | biostudies-arrayexpress
Genomicsena-DATASET-ErasmusMC-13-07-2021-14:23:08:540-67 - samples
Collection of mostly matching primary and recurrent glioblastoma RNA-seq sample pairs, also matching with an earlier DNA sequencing study
EGAD00001007860 | EGA
GenomicsG-SAM: Transcriptional Evolution of Glioblastomas Treated With Standard of Care
Collection of mostly matching primary and recurrent glioblastoma RNA-seq sample pairs, also matching with an earlier DNA sequencing study
EGAS00001005436 | EGA
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