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TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium to investigate the disruption of tolC on the transcriptome
Analysis of the effect of disruption of tolC on the transcriptome of Salmonella enterica serovar Typhimurium
ORGANISM(S): Salmonella typhimurium 
2009-06-03 | E-MEXP-1982 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium to investigate the effects of acrB duisruption
Analysis of effect of disruption of acrB on the transcriptome of Salmonella enterica serovar Typhimurium
ORGANISM(S): Salmonella typhimurium 
2009-06-03 | E-MEXP-1981 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and acrA inactivated Salmonella enterica to investigate the role of acrA in antibiotic resistance and pathogenicity
To investigate the role of acrA in antibiotic resistance and pathogenicity this gene was inactivated by insertion of a kanamycin cassette in strain SL1344 and the results on the transcriptome determined.
ORGANISM(S): Salmonella enterica 
2008-12-31 | E-MEXP-1832 | biostudies-arrayexpress
GenomicsUsing TraDIS-Xpress to find the genes that affect susceptibility to common food preservatives
The mechanisms of action of common food preservatives are poorly understood. As there is a drive to develop alternative preservatives, understanding the mechanisms of action of current preservatives can inform development of novel food preservatives to ensure their efficacy. Here we used TraDIS-Xpre...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2025-03-14 | E-MTAB-14856 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium exposure to triclosan
S. Typhimurium SL1344 was exposed to the minimum inhibitory concentration of triclosan and the transcriptomic response analysed.
ORGANISM(S): Salmonella enterica 
2009-08-28 | E-MEXP-2078 | biostudies-arrayexpress
TranscriptomicsWhole genome \"TraDIS-Xpress\" assay to determine gene roles during growth of E. coli in different concentrations of the antibiotics trimethoprim and sulfamethoxazole
To assay every gene in the E. coli genome to identify those that contribute to increased or decreased susceptibility to the antibiotics trimethoprim and sulfamethoxazole. This will help to define more accurately those bacterial cell mechanisms that contribute to these phenomena and provide informat...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2020-10-19 | E-MTAB-9305 | biostudies-arrayexpress
GenomicsWhole genome TraDIS-Xpress assay to determine gene roles during growth of E. coli in different concentrations of the beta-lactam antibiotic meropenem
The aim of the experiment was to assay every gene in the E. coli genome to identify those that contribute to increased or decreased susceptibility to the beta-lactam antibiotic meropenem. A library of transposon-insertion mutants was grown overnight in the presence or absence of a range of concentra...
ORGANISM(S): Escherichia coli K-12 
2022-06-09 | E-MTAB-11802 | biostudies-arrayexpress
GenomicsInvestigating Biofilm Formation Mechanisms in Salmonella on Fresh Produce Using TraDIS-Xpress
This study investigates the mechanisms employed by Salmonella to colonise and establish itself on fresh produce at critical timepoints following infection. We established an alfalfa infection model and compared the findings to those obtained from glass surfaces. Our research revealed dynamic changes...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2023-11-24 | E-MTAB-13495 | biostudies-arrayexpress
GenomicsHigh resolution chemical-genomics identifies targets for synergistic antibiotics with aztreonam
A whole genome screen was used to assay every gene of Escherichia coli strain BW25113 to identify genes involved in susceptibility to the monobactam (beta-lactam) antibiotic aztreonam. The methodology has been called TraDIS-Xpress, and is a version of TraDIS or Tn-seq. A transposon mutant library c...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2024-07-06 | E-MTAB-11576 | biostudies-arrayexpress
UnknownGenomic and phenotypic characterization of 404 individuals with neurodevelopmental disorders caused by CTNNB1 variants.
Not available
S-EPMC9939054 | biostudies-literature
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