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TranscriptomicsEngineering Material Properties of Transcription Factor Condensates to Control Gene Expression in HEK-293T Cells
Phase separation of biomolecules into condensates is a key mechanism in the spatiotemporal organization of biochemical processes in cells. We systematically engineered light-inducible transcription factor condensates with different material properties and analyzed their influence on transcription ac...
ORGANISM(S): Homo sapiens 
2024-04-01 | E-MTAB-13905 | biostudies-arrayexpress
TranscriptomicsIn vitro effect of the integrine LAMA4 on motility and cluster formation of human chondrocytes
Background: Cluster formation of hypertrophic chondrocytes is a sign of late stage osteoarthritis. In vitro chondrocytes have the ability to migrate on scaffolds. Important for motility issues in cartilage are integrines, part of the extracellular matrix, important for locomotory stimuli. The integr...
ORGANISM(S): Homo sapiens 
2015-12-22 | E-GEOD-68428 | biostudies-arrayexpress
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