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Generation of transcriptomes to provide in-depth expression profiles of human Treg and Tconv from the Naive (CD45RA+CD45RO-) and Memory (CD45RA-CD45RO+) compartments
ORGANISM(S): Homo sapiens 
CD4+CD45.1+ TCR75/Rag-/- T cells (TCR75) were adoptively transferred into CD45.2+ B6 or Foxp3-DTR hosts prior to transplantation of a B/c heart (HTx) in the presence or absence (Rej) of anti-CD154 (day 0, day 7, day 14) and DST (day 0) to induce tolerance. A group of tolerant mice were depleted of T...
ORGANISM(S): Mus musculus 
Aryl hydrocarbon receptor (AhR), is a transcription factor and an environmental sensor and AhR ligands exert varying effects from suppression to exacerbation of inflammation, the reason for which is unclear. In the current study, we demonstrate for the first time that the differential effects of A...
ORGANISM(S): Mus musculus 
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