CD4+CD45.1+ TCR75/Rag-/- T cells (TCR75) were adoptively transferred into CD45.2+ B6 or Foxp3-DTR hosts prior to transplantation of a B/c heart (HTx) in the presence or absence (Rej) of anti-CD154 (day 0, day 7, day 14) and DST (day 0) to induce tolerance. A group of tolerant mice were depleted of T...
ORGANISM(S): Mus musculus