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TranscriptomicsComplex patterns of accessibility discriminate sites of PcG repression, H4K16 acetylation and replication initiation
Full title: Complex patterns of genome accessibility discriminate sites of PcG repression, H4K16 acetylation and replication initiation Histone modifications have been proposed to regulate gene expression in part by modulating DNA accessibility and higher-order chromatin structure. However, there i...
ORGANISM(S): Drosophila melanogaster 
2010-03-16 | E-GEOD-17697 | biostudies-arrayexpress
TranscriptomicsLeishmania major infection-induced changes in the small RNA transcriptome of host macrophages.
Protozoan parasites of the genus Leishmania are the causative agent of leishmaniasis, one of the 13 most important tropical diseases. Leishmania persists as endo-parasite in host macrophages, where it uses multiple strategies to manipulate the microbicidal host cell functions and to escape from the ...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-58369 | biostudies-arrayexpress
MetabolomicsApplication of HPLC-PDA-MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit
INTRODUCTION: Blackcurrant (Ribes nigrum L.) is an excellent example of a “super fruit” with potential health benefits. Both genotype and cultivation environment are known to affect the chemical composition of blackcurrant, especially ascorbic acid and various phenolic compounds. Environmental condi...
2019-02-12 | MTBLS773 | MetaboLights
TranscriptomicsTifa-/- vs Tifa+/+ small intestinal organoids stimulated with water, IL-22, IL-22+ADP-Heptose
Bulk RNA sequencing of small intestinal organoids obtained from germline Tifa-/- versus wild-type littermate control mice stimulated in vitro with IL-22 or IL-22 plus ADP-heptose versus mock control
ORGANISM(S): Mus musculus 
2025-05-01 | E-MTAB-14831 | biostudies-arrayexpress
TranscriptomicsComprehensive Transcriptomic Analysis of BV2 Microglia Following TDP-43 Knockdown Versus Non-Silencing Control
In this study, we investigate how knockdown of the RNA-binding protein TDP-43 alters the transcriptional program of BV2 microglial cells. Aberrant TDP-43 function is a hallmark of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), and while most...
ORGANISM(S): Mus musculus 
2025-07-21 | E-MTAB-15184 | biostudies-arrayexpress
UnknownSoft tissue tumor imaging in adults: whole-body staging in sarcoma, non-malignant entities requiring special algorithms, pitfalls and special imaging aspects. Guidelines 2024 from the European Society of Musculoskeletal Radiology (ESSR).
Not available
S-EPMC11631817 | biostudies-literature
UnknownAn Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies.
Not available
S-EPMC11979094 | biostudies-literature
UnknownSEIS: Insight's Seismic Experiment for Internal Structure of Mars.
Not available
S-EPMC6394762 | biostudies-literature
Unknown2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy.
Not available
S-EPMC8190978 | biostudies-literature
UnknownPerceptions of science, science communication, and climate change attitudes in 68 countries - the TISP dataset.
Not available
S-EPMC11747281 | biostudies-literature
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