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GenomicsMITF ChIP-seq in primary melanocyte and melanoma as a function of oncogenic BRAF
Thousands of enhancers are characterized in the human genome, yet few have been shown important in cancer. Inhibiting oncokinases, such as EGFR, ALK, HER2, and BRAF, is a mainstay of current cancer therapy but is hindered by innate drug resistance mediated by upregulation of the HGF receptor, MET. T...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-50681 | biostudies-arrayexpress
TranscriptomicsHumanMethylation450 (450k) data for 79 rheumatoid arthritis disease discordant monozygotic twin pairs
This project contains genome-wide DNA methylation data generated using the HumanMethylation450 BeadChip (Illumina), for 79 rheumatoid arthritis (RA) discordant monozygotic twin pairs. By investigating disease discordant monozygotic twins, DNA methylation can be assessed without the confounding influ...
ORGANISM(S): Homo sapiens 
2018-07-24 | E-MTAB-6988 | biostudies-arrayexpress
UnknownOpen surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools.
Not available
S-EPMC8322924 | biostudies-literature
UnknownOmnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping.
Not available
S-EPMC6479413 | biostudies-literature
TranscriptomicsDNMT1 Maintains Progenitor Function in Self-Renewing Somatic Tissue
Progenitor cells maintain self-renewing tissues throughout life by sustaining their capacity for proliferation while suppressing cell cycle exit and terminal differentiation. DNA methylation provides a potential epigenetic mechanism for the cellular memory needed to preserve the somatic progenitor s...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-18590 | biostudies-arrayexpress
UnknownResponse to atrial arrhythmias in an atrioventricular synchronous ventricular leadless pacemaker: A case report in a paroxysmal atrial fibrillation patient.
Not available
S-EPMC6301888 | biostudies-literature
UnknownOmnipolar Versus Bipolar Electrode Mapping in Patients With Atrial Fibrillation Undergoing Catheter Ablation.
Not available
S-EPMC11967559 | biostudies-literature
TranscriptomicsCOLO829 treatment with PLX4032 and/or MITF knockdown
Thousands of enhancers are characterized in the human genome, yet few have been shown important in cancer. Inhibiting oncokinases, such as EGFR, ALK, HER2, and BRAF, is a mainstay of current cancer therapy but is hindered by innate drug resistance mediated by upregulation of the HGF receptor, MET. T...
ORGANISM(S): Homo sapiens 
2014-01-14 | E-GEOD-50649 | biostudies-arrayexpress
TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
UnknownDAZL Knockout Pigs as Recipients for Spermatogonial Stem Cell Transplantation.
Not available
S-EPMC10649044 | biostudies-literature
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