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NIH 3T3 fibroblasts that express little detectable levels of the MIF binding receptor CD74 but do express the signalling component CD44 were used for the identification of interacting proteins that are shared by MIF and D-DT. Endogenously expressed MIF and D-DT were tagged at the C-terminus using a s...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-27 | PXD020449 | Pride
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...is work we have induced meningeal lymphatic ablation by decreasing the circulating levels of VEGF-C an...
...rol mice were injected with an AAV9 expressing domains 4 to 7 of murine VEGFR3 coupled to an Ig domain (controls). 5 weeks upon the initial ...
ORGANISM(S): Mus musculus 
2024-07-31 | GSE230709 | GEO
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The ghrelin receptor antagonist [D-Lys3]-GHRP-6 (or PBS control) was administered for two weeks to NOD/SCID mice with PC3 prostate cancer cell line xenografts. Daily intraperitoneal injections of 20 nmoles/mouse/day [D-Lys3]-GHRP-6 significantly reduced xenograft tumour size at day 9 to 14. RNA-sequencin...
ORGANISM(S): Homo sapiens 
2019-11-14 | GSE113799 | GEO
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Testing the effect of seaweed as a novel cost-efficient feed source for Atlantic salmon feed. Fermentation of novel raw materials for fish feed is a new practice with little prior experience of direct relevance to aquaculture and fish farming. In Trial D, an alternative marine compound is included...

2023-06-13 | MTBLS6733 | MetaboLights
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Analysis of gene expression in activation-tagged jaw-d mutant plants. Total RNA was extracted from the aerial parts of two weeks old jaw-d and control plants. Keywords: other
ORGANISM(S): Arabidopsis thaliana 
2003-07-09 | GSE518 | GEO
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Peripheral whole blood transcriptome profiles of pregnant women enrolled in the “Vitamin D Antenatal Asthma Reduction Trial” (VDAART) at enrollment during early pregnancy, and again at 32-38 weeks of gestation. Mothers were enrolled in 2 treatment groups: Intervention group with 4400 IU vitamin D supplem...
ORGANISM(S): Homo sapiens 
2017-02-09 | GSE86200 | GEO
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Controversy surrounds whether vitamin D reduces colorectal cancer (CRC) risk, and/or beneficially impacts ...
...inistered to 50 participants in an intervention study. Blood and NM (sigmoidoscopic biopsy) were sampled after 12 weeks. Transcriptomic analysis (HT12 and RNAseq) of post-treatment biopsies assessed enrichment for candidate genes and GO processes prioritised in the observational study. We identified transcriptomic changes in rectum that are consistent with anti-tumour responses. We then sought blood biomarkers predicting this response using receiver-operator curves and calculation of C-statistic. An independent...
ORGANISM(S): Homo sapiens 
2021-06-22 | GSE157982 | GEO
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Dietary supplementation of vitamin D is commonly recommended to patients with multiple sclerosis (MS). We investigated the effect of 1,25-dihydroxyvitamin-D3 (1,25-(OH)2D3) on the brain proteome in the cuprizone model during remyelination. Mice were demyelinated with dietary cuprizone for 7 weeks. The mi...
ORGANISM(S): Mus musculus (Mouse) 
2017-08-16 | PXD002347 | Pride
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Few data are available that describe how probiotics influence systemic metabolism during endurance exercise. Metabolomic profiling of endurance athletes will elucidate mechanisms by which probiotics may confer benefits to the athlete. In this study, twenty-four runners (20 male, 4 female) were block ...
2021-09-03 | MTBLS1357 | MetaboLights
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Peripheral whole blood transcriptome profiles of pregnant women with normal pregnancy and spontaneous preterm birth from 10-18 weeks of gestational age enrolled in the Vitamin D Antenatal Asthma Reduction Trial (VDAART).
ORGANISM(S): Homo sapiens 
2020-02-10 | GSE142974 | GEO
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