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ProteomicsDifferent Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior Towards the S100β Homodimer
The tumor suppressor protein p53 is a transcription factor that is referred to as the “guardian of the genome” and plays an important role in cancer development. P53 is active as a tetramer; the S100β homodimer binds to the intrinsically disordered C-terminus of p53, affecting its transcriptional ac...
ORGANISM(S): Escherichia coli 
2022-10-14 | PXD029914 | Pride
Cross-linking Intrinsically disordered proteins Tumor suppressor S100β P53 
ProteomicsCross-platform clinical proteomics using the Charité open standard for plasma proteomics (OSPP)
Based on large serum and plasma proteome studies, we generate the Charité Open Peptide Standard for Plasma Proteomics (OSPP), an open, versatile peptide internal standard for targeted and untargeted mass spectrometry-based proteomic studies. The OSPP includes 211 concentration-matched stable-isotope...
ORGANISM(S): Homo Sapiens 
PXD083958 |
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