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GenomicsGlobal Mapping of Histone H3 K4 and K27 Trimethylation: Lineage Fate Determination of Differentiating CD4+ T Cells
Multipotential naïve CD4+ T cells differentiate into distinct lineages including Th1, Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4+ T cells begs the question whether the observed changes reflect terminal differentiation with heritable epigenetic modifications ...
ORGANISM(S): Mus musculus 
2009-01-21 | E-GEOD-14254 | biostudies-arrayexpress
UnknownComparison of overfeeding effects on gut physiology and microbiota in two goose breeds.
Not available
S-EPMC7936201 | biostudies-literature
MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
UnknownSingle nucleotide polymorphisms of nucleotide excision repair and homologous recombination repair pathways and their role in the risk of osteosarcoma.
Not available
S-EPMC4476324 | biostudies-literature
UnknownSingle amino acid mutation of SR-BI decreases infectivity of hepatitis C virus derived from cell culture in a cell culture model.
Not available
S-EPMC5537182 | biostudies-literature
UnknownConstruction and immunogenicity of DNA vaccines encoding fusion protein of porcine IFN- λ 1 and GP5 gene of porcine reproductive and respiratory syndrome virus.
Not available
S-EPMC3884778 | biostudies-literature
TranscriptomicsDetection of single nucleotide variations in expressed exons of the human genome using RNA-Seq
Whole genome re-sequencing is still a costly method to detect genetic mutations that lead to altered forms of proteins and may be associated with disease development. Since the majority of disease-related single nucleotide variations (SNVs) are found in protein-coding regions, we propose to identify...
ORGANISM(S): Homo sapiens 
2009-06-15 | E-GEOD-16190 | biostudies-arrayexpress
ProteomicsHs_C-HPP_Testis_Tricine-SDS-PAGE
CN-CHPP 2015 Testis, Tricine-SDS-PAGE
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005333 | PeptideAtlas
TranscriptomicsMapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription
Insulin (INS) synthesis and secretion from pancreatic M-NM-2 cells are tightly regulated; their deregulation causes diabetes. Here we map INS-associated loci in human pancreatic islets by 4C and 3C techniques and show that the INS gene physically interacts with the SYT8 gene, located over 300 kb ...
ORGANISM(S): Homo sapiens 
2011-02-22 | E-GEOD-25862 | biostudies-arrayexpress
GenomicsGenome-wide mapping of REST-bound sites in human CD4+ T cells
We performed ChIP-seq to identify genome-wide REST (NRSF) binding in the human CD4+ T cells. The data were compared to REST occupancy in additional 15 human cell types analyzed by the ENCODE project (GSE32465) in order to study the dynamics and context-dependent functions of REST-chromatin interacti...
ORGANISM(S): Homo sapiens 
2014-08-06 | E-GEOD-49570 | biostudies-arrayexpress
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