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TranscriptomicsIdentification of intermediate-sized non-coding RNAs involved in the UV-induced DNA damage response in C. elegans
We utilized high-throughput RNA-seq to uncover the intermediate-sized noncoding RNAs invovled in UV-DNA Damage Responses in C. elegans. 450 novel transfrags were discovered, some of which show dramatic expression change between the UV irradiation and control. This study should lead to a better under...
ORGANISM(S): Caenorhabditis elegans 
2012-05-01 | E-GEOD-37063 | biostudies-arrayexpress
GenomicsThe Long Noncoding RNA SNHG1 Regulates both the Local and Distal Genes in Cancer
lncRNAs play important roles in various physiological and pathological processes. However, the detailed molecular mechanisms by which lncRNAs act are still incomplete. Here, we functionally characterized the nuclear-enriched lncRNA SNHG1 which is highly expressed in several types of cancer relative ...
ORGANISM(S): Homo sapiens 
2016-08-20 | E-GEOD-85842 | biostudies-arrayexpress
TranscriptomicsA Long Noncoding RNA Acts as a Tumor Suppressor in Esophageal Squamous Cell Carcinoma
Many long noncoding transcripts are involved in cancer progression. Here, we utilized high-throughput microarray to compare the transcriptome alterations between the KYSE30 cells overexpressing an empty vector and Epist, thus identified 95 and 99 down-regulated and up-regulated genes, respectively. ...
ORGANISM(S): Homo sapiens 
2015-01-09 | E-GEOD-64792 | biostudies-arrayexpress
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