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MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
UnknownExternal validation of a deep learning detection system for glaucomatous optic neuropathy: a real-world multicentre study.
Not available
S-EPMC10698045 | biostudies-literature
UnknownLETM2 regulates mitochondrial function and autophagy in diabetic foot ulcers: implications for oxidative stress and therapeutic targeting.
Not available
S-EPMC12638387 | biostudies-literature
UnknownEfficacy and Safety of Denosumab Biosimilar QL1206 Versus Denosumab in Patients with Bone Metastases from Solid Tumors: A Randomized Phase III Trial.
Not available
S-EPMC9971153 | biostudies-literature
UnknownDiagnostic accuracy of fluorine-18 fluorodeoxyglucose positron emission tomography for suspected primary and postoperative pyogenic spondylitis.
Not available
S-EPMC9830889 | biostudies-literature
UnknownThe selected biomarker analysis in 5 types of uterine smooth muscle tumors.
Not available
S-EPMC6065267 | biostudies-literature
UnknownA Butyrate-Yielding Dietary Supplement Prevents Acute Alcoholic Liver Injury by Modulating Nrf2-Mediated Hepatic Oxidative Stress and Gut Microbiota.
Not available
S-EPMC11395132 | biostudies-literature
UnknownInhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury.
Not available
S-EPMC7957171 | biostudies-literature
ProteomicsProteomic analysis demonstrated transcription factor gene YRR1 deletion in Saccharomyces cerevisiae enhances its resistance to vanillin through the upregulation of transcriptional activator Haa1, coactivator Mbf1, and proteasome assembly chaperone Tma17 expression
Vanillin is one of the major phenolic inhibitors of Saccharomyces cerevisiae in lignocellulosic hydrolysates. Deleting transcription factor gene YRR1 improves vanillin resistance by promoting some translation-related processes that were confirmed at the transcription level in our previous studies. I...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-09 | PXD017738 | Pride
Yrr1  quantitative proteomics  vanillin resistance  bioethanol  saccharomyces cerevisiae 
ProteomicsProteomic analysis demonstrated transcription factor gene YRR1 deletion in Saccharomyces cerevisiae enhances its resistance to vanillin through the upregulation of transcriptional activator Haa1, coactivator Mbf1, and proteasome assembly chaperone Tma17 expression
Vanillin is one of the major phenolic inhibitors of Saccharomyces cerevisiae in lignocellulosic hydrolysates. Deleting transcription factor gene YRR1 improves vanillin resistance by promoting some translation-related processes that were confirmed at the transcription level in our previous studies. I...
ORGANISM(S): Saccharomyces cf. cerevisiae 
2021-09-09 | PXD020951 | Pride
Yrr1  quantitative proteomics  vanillin resistance  bioethanol  saccharomyces cerevisiae 
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