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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
ProteomicscircMAN1A2_009-pulled down proteins in HeLa cells
CircRNA pulldown assays were conducted to identify proteins interacting with circMAN1A2_009. In summary, HeLa cell protein extracts were incubated with biotin-labeled circMAN1A2_009 probes obtained from Tsingke Biotechnology, China, at room temperature for 1h. Subsequently, streptavidin magnetic bea...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052372 | Pride
Circman1a2_009 Hela Pull-down assays 
UnknownJanus adhesive bio-patches with targeted drug delivery enabled anti-bacteria and pro-angiogenesis for dura mater repair.
Not available
S-EPMC11804716 | biostudies-literature
UnknownA Novel Banana Mutant "RF 1" (Musa spp. ABB, Pisang Awak Subgroup) for Improved Agronomic Traits and Enhanced Cold Tolerance and Disease Resistance.
Not available
S-EPMC8496975 | biostudies-literature
GenomicsChIP-Seq of STAT3 in 3iL Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) are isolated from the inner cell mass of the blastocysts. The pluripotent properties of hESCs enable the derivation of cell-types or tissues of different lineages for potential applications such as therapeutics discovery and regenerative medicine. Even though hES...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-MTAB-2042 | biostudies-arrayexpress
GenomicsChIP-Seq of Histone Modifications in 3iL Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) are isolated from the inner cell mass of the blastocysts. The pluripotent properties of hESCs enable the derivation of cell-types or tissues of different lineages for potential applications such as therapeutics discovery and regenerative medicine. Even though hES...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-MTAB-2041 | biostudies-arrayexpress
GenomicsChIP-Seq of OCT4, NANOG, p300 in 3iL Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) are isolated from the inner cell mass of the blastocysts. The pluripotent properties of hESCs enable the derivation of cell-types or tissues of different lineages for potential applications such as therapeutics discovery and regenerative medicine. Even though hES...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-MTAB-2044 | biostudies-arrayexpress
UnknownroX1 and roX2 lncRNAs promote heterochromatinization in intestinal stem cells and impair longevity
Not available
S-SCDT-10_1038-S44319-026-00791-8 | biostudies-other
ProteomicsIP-MS of SpvB and SopD2, four biological replicates in 18 LC-MS/MS experiments.
To screen the host targets of SpvB, we performed IP-MS analyses and measured four biological replicates of paired SpvB and SopD2 samples in 18 LC-MS/MS experiments.
ORGANISM(S): Homo Sapiens 
2023-07-25 | PXD044057 |
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