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ProteomicsClinicopathologic and Proteomic Characteristics of Low-Grade Undifferentiated Spindle Cell SarcomaClinicopathologic and Proteomic Characteristics of Low-Grade Undifferentiated Spindle Cell Sarcoma
We collected 14 low-grade paired Undifferentiated spindle cell sarcoma (USCS) to conduct a comprehensive mass spectrometry (MS) proteomic analysis on USCSs, while also comparing the clinicopathologic characteristics of low-grade USCSs and UPSs. More than 5600 proteins could be identified. Low-grade ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-28 | PXD061644 | Pride
Undifferentiated spindle sarcoma Pathology Diagnosis Soft tissue tumor Molecular diagnosis Proteomic characteristic Biomarker 
ProteomicsTGM2-mediated histone serotonylation promotes HCC progression via MYC signalling pathway
TGM2 IP-MS was performed in MHCC-97H cells to screen the interactors of TGM2. 5-PT pulldown-MS was perfromed in MHCC-97H cells to identify proteins modified by serotonylation.
ORGANISM(S): Homo Sapiens 
2024-12-06 | PXD058674 |
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045945 |
ProteomicsO-GlcNAc Glycosylation 4D-Label free Quantitative Proteomics Bioinformatics Analysis Report
O-linked β-N-acetylglucosamine (O-GlcNAc) modification is a dynamic post-translational modification that involves the reversible attachment of N-acetylglucosamine to serine or threonine residues of nuclear, cytoplasmic, and mitochondrial proteins. This modification is critical for regulating cellula...
ORGANISM(S): Homo Sapiens 
2025-11-26 | PXD066348 |
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