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Low molecular weight proteins (LMWPs) in the bloodstream participate in various biological processes and are closely associated with disease status, whereas identification of serous LMWPs remains a great technical challenge due to the wide dynamic range of protein components. In this study, we const...
ORGANISM(S): Homo sapiens (Human) 
2022-07-11 | PXD034184 | Pride
Clinical use of intraoperative auto-transfusion requires the removal of platelets and plasma proteins due to the pump-based suction and water-soluble anticoagulant administration, which causes dilutional coagulopathy. Herein, we develop a carboxylated and sulfonated heparin-mimetic polymer-modified ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-23 | PXD044005 | Pride
The endogenous RNA substrates of Translin-TRAX complexes (also known as C3POs) and how they regulate diverse biological processes remain unknown. Here we show that Translin and TRAX do not play a significant role in RNAi in the filamentous fungus Neurospora crassa. Instead, the Neurospora C3PO compl...
ORGANISM(S): Neurospora crassa 
A variety of small RNAs, including the Dicer-dependent miRNAs and the Dicer-independent Piwi-interacting RNAs, associate with Argonaute family proteins to regulate gene expression in diverse cellular processes. These two species of small RNA have not been found in fungi. Here, by analyzing small RN...
ORGANISM(S): Neurospora crassa 
Larix olgensis is an economically important tree species native to northeastern China. Its somatic embryogenesis (SE) system is both efficient and stable, and this permits varieties with desirable qualities to be reproduced rapidly. Here, isobaric labeling via tandem mass tags was used to conduct a ...
ORGANISM(S): Larix 
2023-02-24 | PXD040378 |
The development of an antithrombotic surface that prevents coagulation activation without interfering with hemostasis is the “holy grail” for blood-contacting devices. Such an advance would restrain device-induced thrombogenesis, and decrease the need for anticoagulant use in conjunction with device...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054476 | Pride
Influenza A virus (IAV) lacks the enzyme for adding 5’ caps to its RNAs, and thus snatches the 5’ ends of host capped RNAs to prime transcription. Neither the preference of the host RNA sequences snatched, nor the effect of “cap-snatching” on host processes has been completely defined. Previ...
ORGANISM(S): Homo sapiens 
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