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MetabolomicsCHOICE clinical weight loss study
Not available
ORGANISM(S): Homo sapiens;Rattus norvegicus 
ST000661 | MetabolomicsWorkbench
MetabolomicsMetabolomics of bariatric weight loss
Not available
ORGANISM(S): Homo sapiens 
ST000743 | MetabolomicsWorkbench
TranscriptomicsThe effect of progressive weight loss on metabolic function
The purpose of this study was to evaluate the effect of progressive weight loss (5, 10, 15% weight loss) on metabolic function such as multi-organ insulin sensitivity and beta-cell function in obese people. We conducted microarray analysis to determine the effect of progressive weight loss on adipos...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-GEOD-70529 | biostudies-arrayexpress
MetabolomicsWeight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels.
Not available
ORGANISM(S): Homo sapiens 
ST000502 | MetabolomicsWorkbench
Proteomics,MultiomicsPlasma Proteome Profiling Reveals the Effects of Weight Loss on the Apolipoprotein Family and Systemic Inflammation Status
Sustained weight loss is the preferred intervention in a wide range of metabolic conditions, but the effects on an individual´s health state remain ill-defined and controversial. Here, we investigate the plasma proteomes of a cohort of 43 obese individuals that had undergone eight weeks of weight lo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-02 | MSV000080596 | MassIVE
TranscriptomicsWeight loss in obesity reduces colorectal inflammation
The hypothesis tested in the present study was The effect fo weight loss by dietary intervention with very low calorie diet on colorectal inflammatory genes and genepathways. The study results have shown that a 10% weight loss in obese women down-regulated inflammatory and cancer gene pathways. In ...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-20931 | biostudies-arrayexpress
MetabolomicsGut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice
Calorie restriction (CR) and fasting are common approaches to weight reduction, but the maintenance is difficult after resuming food consumption. Meanwhile, the gut microbiome associated with energy harvest alters dramatically in response to nutrient deprivation. Here, we reported that CR and high-f...
2022-04-01 | MTBLS4431 | MetaboLights
TranscriptomicsTranscription profiling of human skeletal muscle from morbidly obese patients before and after gastric bypass surgery to identify genes responsive to weight loss.
Obesity results from a chronic imbalance between energy intake and energy expenditure, with excess calories stored as fat. As such, weight loss has long been considered as a primary goal of treatment for obesity. A surgical treatment of severe obesity such as gastric bypass provides the most dramati...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-5109 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human adipose Tissue during Weight Loss
We investigated the regulation of adipose tissue (AT) gene expression during different phases of a dietary weight loss program and its relationship with insulin sensitivity. Obese women followed a weight reduction program composed of an energy restriction phase (ER) with a 4-week very-low-calorie di...
ORGANISM(S): Homo sapiens 
2009-05-16 | E-GEOD-11975 | biostudies-arrayexpress
MetabolomicsBone loss with aging is independent of gut microbiome in mice.

Emerging evidence suggests a significant role of gut microbiome in bone health. Aging is well recognized as a crucial factor influencing the gut microbiome. In this study, we investigated whether age-dependent microbial change contributes to age-related bone loss in CB6F1 mice. The bone phenotype...

2024-09-06 | MTBLS10321 | MetaboLights
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