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MetabolomicsSerum Predose Metabolic Profiling For Prediction Of Rosuvastatin Pharmacokinetic Parameters In Healthy Volunteers
Rosuvastatin is a quite known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery diseases prevention. There is substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to variation in the correspondi...
2021-10-29 | MTBLS3128 | MetaboLights
TranscriptomicsExpression quantitative trait loci (eQTL) analysis of Brassica rapa under varying soil phosphorus (P) supplies
The aim of this study was to identify eQTL in Brassica rapa grown under altered soil phosphorus (P) supply, to understand better the genetic architecture of P-use efficiency (PUE) in plants. Recombinant inbred lines (RILs) of the BraIRRI mapping population were grown at adequate and growth-limiting ...
ORGANISM(S): Brassica rapa 
2011-06-29 | E-GEOD-27052 | biostudies-arrayexpress
TranscriptomicsCirculating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma
Global microRNA expression profiling of serum were collected using Agilent miRNA microarrays (G4471A Human, Amadid 29297, Sanger 14) carrying 887 individual human miRNA probes. Two different sources of RNA were analyzed: serum from NMRI-nu/nu mice carrying a xenograft tumor derived from human prima...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-34052 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood from acute promyelocytic leukemia patients using different differentiating agents
Differentiating agents have been proposed to overcome the impaired cellular differentiation in acute myeloid leukemia (AML). However, only the combinations of all-trans retinoic acid or arsenic trioxide with chemotherapy have been successful, and only in treating acute promyelocytic leukemia (also c...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-TABM-925 | biostudies-arrayexpress
UnknownGene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
Not available
S-EPMC10651736 | biostudies-literature
UnknownGene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
Not available
S-EPMC7641978 | biostudies-literature
UnknownNovel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Not available
S-EPMC6005576 | biostudies-literature
UnknownA multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Not available
S-EPMC6644157 | biostudies-literature
UnknownA Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Not available
S-EPMC5985266 | biostudies-literature
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