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TranscriptomicsTranscription profiling of Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate
Each experiment consisted in an artesunate-free culture (control) and an artesunate treated culture. For each time point explored, cDNA from parasites with and without the drug were labeled with different cyanines, mixed and hybridized. To analyse dynamic transcriptome alterations, two pilot experim...
ORGANISM(S): Plasmodium falciparum 
2008-06-01 | E-MEXP-1435 | biostudies-arrayexpress
TranscriptomicsSADE analysis of microdissected kidney
Libraries generated from microdissected kidney samples from the healthy pole of cancerous kidneys. Donors were from either sex. Libraries were generated using Sau3A I as anchoring enzyme. Data are provided after removal of linker derived sequences. Keywords: other
ORGANISM(S): Homo sapiens 
2003-11-13 | E-GEOD-694 | biostudies-arrayexpress
TranscriptomicsTimEX from human embryonic stem cells, mesenchymal stem cells, and erythroid cells
The organization of mammalian DNA replication is poorly understood. We have produced genome-wide high-resolution dynamic maps of the timing of replication in human erythroid, mesenchymal and embryonic stem cells using TimEX, a method that relies on gaussian convolution of massive, highly redundant d...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18679 | biostudies-arrayexpress
TranscriptomicsDNA validation of LAB 2k v2
To study their metabolic potential in natural ecosystems, we developed a species-independent LAB microarray, containing 2,269 30-mer oligonucleotides, and targeting 406 genes that play a key role in the production of sugar catabolites, bacteriocins, exopolysaccharides, and aromas, in probiotic and b...
ORGANISM(S): Lactobacillus johnsonii 
2009-10-20 | E-GEOD-9082 | biostudies-arrayexpress
TranscriptomicsLarge-Scale Expression Analysis Reveals Distinct microRNA Profiles at Different Stages of Human Neurodevelopment
Background: MicroRNAs (miRNAs) are short non-coding RNAs predicted to regulate one third of protein-coding genes via mRNA targeting. In conjunction with key transcription factors, such as the repressor REST (RE1 silencing transcription factor), miRNAs play crucial roles in neurogenesis, which requir...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-15888 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of ethanol-stressed vs. non-stressed culture
The yeast Saccharomyces cerevisiae is well known for its high ethanol production performances. An original fermentation process that allows the yeast S. cerevisiae to produce in less than 45 h more than 150 g/l ethanol (i.e. 18.9°GL) was set up in our laboratory [1]. Under this condition, the yeast ...
ORGANISM(S): Saccharomyces cerevisiae 
2009-09-01 | E-GEOD-15493 | biostudies-arrayexpress
TranscriptomicsOdontoblast-like cells and dental pulp fibroblasts stimulated with LTA, poly(I:C) and LPS.
Odontoblasts and fibroblasts are suspected to influence the innate immune response triggered in the dental pulp by micro-organisms that progressively invade the human tooth during the carious process. To determine whether they differ in their responses to oral pathogens, we performed a systematic co...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9560 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of drought treated P.euphratica
Plantlets of P. euphratica (clone B2) were obtained by in vitro culture. After ex vitro acclimation, they were transferred and acclimated to greenhouse conditions and transplanted into 7.5L-pot filled with peat-sand mix (50/50 V/V) and were pruned (following some leaf shedding due to transplantation...
ORGANISM(S): Populus euphratica 
2005-03-01 | E-MEXP-276 | biostudies-arrayexpress
TranscriptomicsYarrowia lipolytica fed-batch biolipid production.
Time-course transcriptomic profilling of the oleaginous yeast Yarrowia lipolytica, during a controlled fed-batch. A nitrogen limitation was applied during the course of the fed-batch to initiate de novo biolipid synthesis. Dual staining, one replicate per slide. On each slide, a time point sample an...
ORGANISM(S): Yarrowia lipolytica 
2011-05-15 | E-GEOD-29046 | biostudies-arrayexpress
TranscriptomicsGene expression signature of cerebellum hypoplasia in a mouse model of Down syndrome (Part I).
We designed a large scale gene expression study in Ts1Cje mice between P0 and P10 in order to measure the effects of trisomy 21 on a large number of samples (56 in total) in a tissue that is affected in Down syndrome (the cerebellum) and to quantify the defect during development in order to correlat...
ORGANISM(S): Mus musculus 
2009-03-31 | E-GEOD-11448 | biostudies-arrayexpress
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