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TranscriptomicsTranscription profiling of chicken develomental time series of the retinal pigment epithelia
Purpose: The morphology of the RPE shows minimal change as the neural retina and choriocapillaris differentiate. Nonetheless, initial studies of barrier-related proteins suggest extensive remodeling of the RPE in response to this changing environment. A genomic approach was used to investigate the e...
ORGANISM(S): Gallus gallus 
2008-11-08 | E-GEOD-7176 | biostudies-arrayexpress
ProteomicsNovel splicing and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts
Adenovirus is a common human pathogen that relies on host cell processes for transcription and processing of viral RNA and protein production. Although adenoviral promoters, splice junctions, and cleavage and polyadenylation sites have been characterized using low-throughput biochemical techniques o...
ORGANISM(S): Homo sapiens (Human) 
2022-08-30 | PXD034464 | Pride
Targeted ms Splicing Adenovirus 
ProteomicsIdentifying host factors associated with DNA replicated during virus infection
Viral DNA genomes replicating in cells encounter a myriad of host factors that facilitate or hinder viral replication. Viral proteins expressed early during infection modulate host factors interacting with viral genomes, recruiting proteins to promote viral replication, and limiting access to antivi...
ORGANISM(S): Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) Homo sapiens (Human) Vaccinia virus WR Herpesvirales 
2017-10-04 | PXD007741 | Pride
Virus infection / dna replication / dna repair / intrinsic defense 
ProteomicsTime-resolved Global and Chromatin Proteomics during Herpes Simplex Virus (HSV-1) Infection
Herpes simplex virus (HSV-1) lytic infection results in global changes to the host cell proteome and the proteins associated with host chromatin. We present a system level characterization of proteome dynamics during infection by performing a multi-dimensional analysis during HSV-1 lytic infection o...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) 
2017-02-10 | PXD005467 | Pride
Post-translational modifications (ptms) Viral life cycle Chromatin dynamics Herpes simplex virus (hsv-1) infection Lytic infection Phosphoproteomics Histone modifications 
UnknownCabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial.
Not available
S-EPMC4110249 | biostudies-literature
UnknownInteraction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity
Not available
S-SCDT-EMBOR-2020-52145V1 | biostudies-other
UnknownThe SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress
Not available
S-SCDT-10_1038-S44318-024-00137-X | biostudies-other
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