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MetabolomicsHigh-resolution LC-MS/MS lipidomics characterization of wild-type and ATG7-deficient mouse renal proximal tubule cells
This study provides an untargeted lipidomics investigation of ATG7-deficient (cKO) mouse renal proximal tubule cells compared to wild-type (WT) controls to evaluate lipidomic alterations associated with autophagy deficiency. Lipids were extracted from cell culture wells using a single-phase isopropa...
2026-09-30 | MTBLS15861 | MetaboLights
UnknownQuantification of how mechanical ventilation influences the airborne infection risk of COVID-19 and HVAC energy consumption in office buildings.
Not available
S-EPMC9528863 | biostudies-literature
ProteomicsChanges to SUMO2 conjugation during Influenza virus infection of cultured cells
Dynamic SUMO modifications of diverse cellular protein groups are critical to orchestrate resolution of stresses such as genome damage, hypoxia or proteotoxicity. Defense against pathogen insult (usually reliant upon host recognition of ‘non-self’ nucleic acids), is also modulated by SUMO, but the u...
ORGANISM(S): Homo sapiens (Human) 
2019-08-12 | PXD014136 | Pride
Ns1 Influenza Sumo 
TranscriptomicsSingle-cell RNA-sequencing of mouse thymic epithelial cells across the first year of life
The thymus shapes the T cell receptor repertoire, and is one of the first organs to rapidly age, with gross changes in cellularity and architecture. To resolve the nature of these changes we used SMART-Seq2 on FACS purified thymic epithelial cells (TEC) across the first year of mouse life. We sorted...
ORGANISM(S): Mus musculus 
2020-09-14 | E-MTAB-8560 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Caenorhabditis elegans whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells.
Tissue specific microarray data is obtained by generating a whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells (Roy et al. 2002). Different lines were compared: SV911 (control), SV912 (CY...
ORGANISM(S): Caenorhabditis elegans 
2011-11-25 | E-TABM-886 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of sorted epitope-specific autoreactive B cells from healthy donor buffy coats
The aim of the experiment is to identify candidate genes to phenotype epitope-specific autoreactive B cells. These genes could serve as markers to delineate further populations of autoreactive B cells that were shown to be key players in regulating autoimmunity and in explaining B cell selection.
ORGANISM(S): Homo sapiens 
2023-08-31 | E-MTAB-13291 | biostudies-arrayexpress
Transcriptomicssingle-cell RNA-seq of of dermal fibroblasts
Dermal fibroblasts from human, rhesus macaque, mouse and rat, stimulated with dsRNA (poly I:C) in a time course of 0,2,4 and 8 hours, profiled using the Smart-seq2 protocol.
The innate immune response - the expression programme that is initiated once a pathogen is sensed - is known to be variable...
ORGANISM(S): Macaca mulatta 
2018-07-06 | E-MTAB-5920 | biostudies-arrayexpress
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