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ProteomicsMYC as a Key Regulator of Protein Synthesis: Characterization of Downstream Targets in Multiple Myeloma
Multiple myeloma (MM) is a malignant plasma cell disorder and frequently characterized by the 16 dysregulation of the MYC oncogene, which is associated with poor prognosis and disease progression. While MYC's involvement in transcriptional regulation is well-established, the functional role of MYC t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-15 | MSV000092169 | MassIVE
ProteomicsHypoxia-Induced Regulation of the Proteome in Multiple Myeloma Cell Lines
Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low oxygen levels (1-6% O2), known as hypoxia. For MM cells, hypoxia is a physiologic featur...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD030239 | Pride
Human Multiple myeloma Plasma cells Hypoxia Lc-ms/ms 
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