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GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
UnknownTargeting Stat3 with conditional knockout or PROTAC technology alleviates renal injury by Limiting pyroptosis.

Background

Acute kidney injury (AKI) is a critical clinical syndrome with high morbidity, mortality, and no effective treatment in clinical practice. The role of the Signal Transducer and Activator of Transcription 3 (Stat3) in AKI remains controversial, and its complex regulatory mechanisms...
S-EPMC12136849 | biostudies-literature
UnknownCOVID-19 immune features revealed by a large-scale single-cell transcriptome atlas.
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent immune cells is not complete. We applied single-cell RNA sequencing to 284 samples from 196 COVID-19 patients and controls ...
S-EPMC7857060 | biostudies-literature
UnknownExtracting the femtometer structure of strange baryons using the vacuum polarization effect.
One of the fundamental goals of particle physics is to gain a microscopic understanding of the strong interaction. Electromagnetic form factors quantify the structure of hadrons in terms of charge and magnetization distributions. While the nucleon structure has been investigated extensively, data on...
S-EPMC11470094 | biostudies-literature
UnknownProbing CP symmetry and weak phases with entangled double-strange baryons.
Though immensely successful, the standard model of particle physics does not offer any explanation as to why our Universe contains so much more matter than antimatter. A key to a dynamically generated matter-antimatter asymmetry is the existence of processes that violate the combined charge conjugat...
S-EPMC9159954 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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