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UnknownPrognostic and Predictive Value of Immune-Related Gene Expression Signatures vs Tumor-Infiltrating Lymphocytes in Early-Stage ERBB2/HER2-Positive Breast Cancer: A Correlative Analysis of the CALGB 40601 and PAMELA Trials.
Not available
S-EPMC9857319 | biostudies-literature
UnknownIsoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis.
Not available
S-EPMC7044113 | biostudies-literature
TranscriptomicsTranscription profiling of mouse transgenics (3 mo) inducibly expresssing human alpha1-antitrypsin in the liver
In the classical form of α1antitrypsin deficiency a mutant protein accumulates in a polymerized form in the ER of liver cells causing liver damage and carcinogenesis by a gain-of-toxic function mechanism. Recent studies have indicated that the accumulation of mutant α1antitrypsin Z in the ER spec...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8599 | biostudies-arrayexpress
TranscriptomicsSynthetic circuit identifies subpopulations with sustained memory of DNA damage
Differential responses to stimuli can affect how cells succumb to disease. In yeast, DNA damage can create heterogeneous responses. To delineate how a response contributes to a cell's future behavior, we constructed a transcription-based memory circuit that detects DNA repair to isolate subpopulatio...
ORGANISM(S): Saccharomyces cerevisiae 
2012-03-02 | E-GEOD-36210 | biostudies-arrayexpress
TranscriptomicsMicroRNA signatures predict Estrogen receptor, Progesterone receptor and HER2/neu receptor status in Breast Cancer
Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the estrogen, progesterone and HER2/neu receptors which characterise clinically distinct breast tumors have been shown to change during disease progression and in response to system...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15885 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of transgenic mice overexpressing human alpha-synuclein under the PDGF beta promoter to wildtype littermates at 3 months and 9 months of age.
Microarray comparison of transgenic mice overexpressing human alpha-synuclein under the PDGF beta promoter to wildtype littermates at 3 months and 9 months of age. RNA was extracted from substantia nigral cells that were isolated by laser capture microdissection.
ORGANISM(S): Mus musculus 
2007-12-20 | E-MEXP-1383 | biostudies-arrayexpress
TranscriptomicszzYra1 co-IPed RNA vs. Total RNA (zzYra1IP_v_TotalRNA)
Comparison of cDNA from RNA IPed with zzYra1 to that from total RNA; resulting analysis gives Yra1 binding level relative to total abundance for each mRNA
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-27 | E-GEOD-101 | biostudies-arrayexpress
UnknownAssessment of vascularity in glioblastoma and its implications on patient outcomes.
Not available
S-EPMC5479489 | biostudies-literature
GenomicsGenomewide Association Study of Alcohol Use and Alcohol Use Disorder in Australian Twin-Families (OZ-ALC GWAS)

The Australian twin-family study of alcohol use disorder (OZALC study) derives from telephone diagnostic interview studies of two general population volunteer cohorts of Australian twins (cohort 1, mostly born 1940-1964; cohort 2, born 1964-71) and the spouses of the former cohort - a total of ov...

phs000181.v1.p1 | EGA
TranscriptomicsHuman CD34+-derived erythoblast (polychromatophilic and orthochromatic) response to co-culture with Plasmodium falciparum 3D7
Global, genomic responses of erythrocytes to infectious agents have been difficult to measure, because these cells are e-nucleated. We have previously demonstrated that in vitro matured, nucleated erythroblast cells at the orthochromatic stage can be efficiently infected by the human malaria parasit...
ORGANISM(S): Homo sapiens 
2011-05-30 | E-GEOD-24849 | biostudies-arrayexpress
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