Sort   by:  
 Page size 
ProteomicsA ubiquitin-based effector-to-inhibitor switch coordinates brain, craniofacial, and skin development
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a posttranslational pathway that drives early ectodermal ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-14 | MSV000090711 | MassIVE
TranscriptomicsCell fate determination by ubiquitin-dependent regulation of ribosome function
Metazoan development depends on accurate execution of differentiation programs that allow pluripotent stem cells to adopt specific fates. Differentiation is brought about by global changes to chromatin architecture and transcriptional networks, yet whether other regulatory events support cell fate d...
ORGANISM(S): Homo sapiens 
2015-09-24 | E-GEOD-62123 | biostudies-arrayexpress
TranscriptomicsCell fate determination by ubiquitin-dependent regulation of translation
Metazoan development depends on accurate execution of differentiation programs that allow pluripotent stem cells to adopt specific fates. Differentiation is brought about by global changes to chromatin architecture and transcriptional networks, yet whether other regulatory events support cell fate d...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-62247 | biostudies-arrayexpress
ProteomicsNix Interacts with WIPI2 to Induce Mitophagy
Determining what autophagy proteins bind to the MER domain of Nix
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-30 | MSV000092324 | MassIVE
UnknownNix Interacts with WIPI2 to Induce Mitophagy
Not available
S-SCDT-10_15252-EMBJ_2023113491 | biostudies-other
ProteomicsShared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases
UBA1 initiates most cellular ubiquitin signaling by activating and transferring ubiquitin to tens of E2 enzymes. Clonally acquired UBA1 missense mutations cause a severe inflammatory-hematologic overlap disease called VEXAS (vacuoles, E1, X-linked autoinflammatory, somatic) syndrome. Despite extensi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092914 | MassIVE
UnknownShared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases
Not available
S-SCDT-10_1038-S44318-024-00046-Z | biostudies-other
Sort   by:  
 Page size