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UnknownLenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Not available
S-EPMC4067945 | biostudies-literature
TranscriptomicsRNA-seq of coding RNA of Actinoplanes sp. SE50/110 to analyze gene function of alternative sigma factor gene ACSP50_0507
Cultivation in maltose minimal media and sampling at different time point (t2 = 96h; t3=118h; t4 = 142h; t5 = 166h) of Actinoplanes sp. SE50/110 empty vector control and Actinoplanes sp. SE50/110 ACSP50_0507 overxepression mutant. RNAseq material and methods
ORGANISM(S): Actinoplanes sp. SE50/110 
2024-07-22 | E-MTAB-13644 | biostudies-arrayexpress
UnknownmiR-424/503 modulates Wnt/β-catenin signaling in the mammary epithelium by targeting LRP6
Not available
S-SCDT-EMBOR-2021-53201V1 | biostudies-other
ProteomicsA ubiquitin-based effector-to-inhibitor switch coordinates brain, craniofacial, and skin development
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a posttranslational pathway that drives early ectodermal ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-14 | MSV000090711 | MassIVE
TranscriptomicsTumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase
Deregulated expression of MYC is a driver of colorectal carcinogenesis, necessitating novel strategies to inhibit MYC function. The ubiquitin ligase HUWE1 (HECTH9, ARFBP1, MULE) associates with both MYC and the MYC-associated protein MIZ1. We show here that HUWE1 is required for growth of colorecta...
ORGANISM(S): Homo sapiens 
2014-10-21 | E-GEOD-59223 | biostudies-arrayexpress
ProteomicsEffects of Navitoclax and Venetoclax on changes in the proteome of mouse pancreas in a mouse model of chronic pancreatitis
Effects of two Bcl-2 protein inhibitors Navitoclax and Venetoclax on changes in the proteome of the mouse pancreas (Mus musculus C57BL6/J, males) in a mouse model of cerulein-induced chronic pancreatitis.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000095776 | MassIVE
TranscriptomicsAn integrated approach combining RNA-seq, Ribo-seq and Proteomics identifies the coding potential of Mycobacterium abscessus
The objective of this study is to develop an integrated map for the M. abscessus ATCC19977 organism. Among the data types contributing to the development of this map are next-generation RNA-sequencing, differential RNA-sequencing, ribosome profiling, and mass spectrometry. The design of the study co...
ORGANISM(S): Mycobacterium abscessus ATCC 19977 
2016-03-30 | E-GEOD-72996 | biostudies-arrayexpress
TranscriptomicsIntra-macrophage transcriptome of Salmonella enterica serovar Typhimurium 4/74 using strand-specific RNA-seq
Bacterial transcription is controlled by many transcription factors and promoters. Currently many promoters are mapped only in in vitro conditions. We use an intra-macrophage model to map the promoters and their expression in vivo. Transcriptome analysis of S.Typhimurium 4/74 within macrophages usin...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2015-07-30 | E-GEOD-59945 | biostudies-arrayexpress
MetabolomicsGNPS - Dataset Creation from GNPS Molcular Networking - 89895d4507c84596a6a01685bfd8acd4
Molecular Networking of fungal culture extracts from T. erinacei analyzed by LC-MS in positive ion mode
ORGANISM(S): Trichophyton Erinacei (ncbitaxon:523106) 
2021-04-29 | MSV000087335 | GNPS
UnknownNMDA receptor gene variations as modifiers in Huntington disease: a replication study.
Not available
S-EPMC3186947 | biostudies-literature
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