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TranscriptomicsGene Expression Analysis in the Thalamus and Cerebrum of Horses Experimentally Infected with West Nile Virus
The purpose of this experiment was to further our understanding of gene expression in the central nervous system (thalamus and cerebrum) after exposure to West Nile virus. To that end, three different analyses were performed. The first examined differences in gene expression between horses not va...
ORGANISM(S): Equus caballus 
2011-08-31 | E-GEOD-30347 | biostudies-arrayexpress
TranscriptomicsLIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (HTS)
LIN28 is a conserved RNA binding protein implicated in pluripotency, reprogramming and oncogenesis. Previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, here we elucidate distinct roles of LIN28 regulation via its direct messenger RNA (mRNA) targets. Through cross-linking...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39872 | biostudies-arrayexpress
TranscriptomicsGene expression in murine pancreatic tumor tissues in response to the blockade of macrophage colony-stimulating factor receptor (CSF1R) signal
Analysis of responses induced upon the blockade of CSF1R signaling at the gene expression level. Hypothesis of this study was that CSF1R signal blockade alters the local immune responses in a murine pancreatic tumor model. Results provide important information on changes in the immune responses in t...
ORGANISM(S): Mus musculus 
2014-05-15 | E-GEOD-57686 | biostudies-arrayexpress
TranscriptomicsChromatin interactions involving super-enhancers associate with specific expression patterns of target genes
Super-enhancers may regulate target genes through chromatin looping. We connected super-enhancers in the K562 chronic myelogenous leukemia cell line with chromatin interactions identified from Chromatin Interaction Analysis with Paired-End Tag (ChIA-PET) data. Gene expression at proximal elements th...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-GEOD-77125 | biostudies-arrayexpress
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
TranscriptomicsRemodeling of synaptic transmission genomic fabrics in the hypothalamic arcuate nucleus of a rat female model of infantile spasms
We profiled the whole transcriptomes of female rat hypothalamic arcuate nuclei to determine the remodeling of the genomic fabrics responsible for the glutamatergic, GABAergic, dopaminergic, cholinergic and serotonergic transmission in epilepsy and recovery following different treatments. The rats we...
ORGANISM(S): Rattus norvegicus 
2016-07-20 | E-GEOD-84585 | biostudies-arrayexpress
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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