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TranscriptomicsMouse granule cell neuron transcriptional response to wild-type West Nile virus (WNV-NY) and mutant virus WNV E218A (microRNA)
The purpose is to obtain samples for transcriptional analysis in triplicate wells using wild type West Nile virus (WNV NY99 clone 382; WNVWT) and mutant virus (WNVE218A) in mouse granule cell neurons. This data set comprises two complete biological replicate experiments conducted in the same conditi...
ORGANISM(S): Mus musculus 
2015-04-29 | E-GEOD-68381 | biostudies-arrayexpress
TranscriptomicsMouse cortical neuron transcriptional response to wild-type West Nile virus (WNV NY99 clone 382) and mutant virus WNV E218A [microRNA]
The purpose is to obtain samples for transcriptional analysis in triplicate wells using wild type West Nile virus (WNV NY99 clone 382; WNVWT) and mutant virus (WNVE218A) in mouse cortical neurons. This data set comprises two complete biological replicate experiments conducted in the same conditions ...
ORGANISM(S): Mus musculus 
2015-04-04 | E-GEOD-67474 | biostudies-arrayexpress
TranscriptomicsMouse cortical neuron transcriptional response to wild-type West Nile virus (WNV-NY) and mutant virus WNV E218A [mRNA]
The purpose is to obtain samples for transcriptional analysis in triplicate wells using wild type West Nile virus (WNV NY99 clone 382; WNVWT) and mutant virus (WNVE218A) in mouse cortical neurons. This data set comprises two complete biological replicate experiments conducted in the same conditions ...
ORGANISM(S): Mus musculus 
2015-04-04 | E-GEOD-67473 | biostudies-arrayexpress
TranscriptomicsMouse granule cell neuron transcriptional response to wild-type West Nile virus (WNV-NY) and mutant virus WNV E218A (mRNA)
The purpose is to obtain samples for transcriptional analysis in triplicate wells using wild type West Nile virus (WNV NY99 clone 382; WNVWT) and mutant virus (WNVE218A) in mouse granule cell neurons. This data set comprises two complete biological replicate experiments conducted in the same conditi...
ORGANISM(S): Mus musculus 
2015-04-29 | E-GEOD-68380 | biostudies-arrayexpress
TranscriptomicsDevelopment of distinct gene expression signature in neurons from different regions of the brain
We have performed microarray expression profiling of mouse primary neurons (cortical neurons and granule cell neurons) to model molecular networks and define whether distinct antiviral IFN responses occurred in neurons corresponding to different brain regions. Primary mouse cortical neurons and gran...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-42727 | biostudies-arrayexpress
TranscriptomicsGenome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function [cultured cortical neurons]
To examine potential differences in activity-dependent gene expression, we analyzed mRNA expression in cultured neurons isolated from Wild-type vs MeCP2 S421A mice at 0 (unstimulated), 1 or 6 hours after membrane depolarization by exposure to high extracellular KCl (55mM) All mice were male litterma...
ORGANISM(S): Mus musculus 
2011-09-07 | E-GEOD-31849 | biostudies-arrayexpress
UnknownProbing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.
Not available
S-EPMC5807211 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis treated with sugars (glucose, mannose) and abcissic acid
The aim of the experiment is to determine sugar and ABA responsive gene expression in Arabidopsis.
ORGANISM(S): Arabidopsis thaliana 
2005-10-01 | E-MEXP-475 | biostudies-arrayexpress
GenomicsTranscriptional and Epigenetic Dynamics During Specification of Human Embryonic Stem Cells
Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the epigenetic mechanisms that facilitate cellular transitions in a human context. To that end, we performed comprehensive transcriptional and epigenetic profiling of early populations derived through direct...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-46130 | biostudies-arrayexpress
GenomicsGenome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function [ChIP-Seq]
Autism spectrum disorders such as Rett syndrome (RTT) have been hypothesized to arise from defects in experience-dependent synapse maturation. RTT is caused by mutations in MECP2, a nuclear protein that becomes phosphorylated at S421 in response to neuronal activation. We show here that disruption o...
ORGANISM(S): Mus musculus 
2011-09-08 | E-GEOD-31951 | biostudies-arrayexpress
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