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ProteomicsStructural determinants of heparinâ??transforming growth factor-β1 interactions and their effects on signalling
Transforming growth factor-Ã?1 (TGF-Ã?1, Uniprot: P01137) is a heparin-binding protein that has been implicated in a number of physiological processes, including the initiation of chondrogenesis by human mesenchymal stem cells (hMSCs). Here, we identify the molecular features in the protein and in...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-19 | MSV000079921 | MassIVE
TranscriptomicsHuman Bone Marrow Stromal Cells cultured on polymer scaffolds with varied properties
Microarray analysis was used to evaluate expression differences from a single donor human bone marrow stromal cells (hBMSCs) as a function of varied polymer-based tissue engineering scaffolds. The results revealed that gene expression patterns of hBMSCs grouped according to scaffold. A library of sc...
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-50743 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine mesenchymal stem cells during differentiation to osteoblasts, treated with tofacitinib or baricitinib against vehicle control
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, characterized by synovial hyperplasia and progressive joint destruction. For treating inflammatory diseases, such as RA, the Janus kinase (JAK)-mediated signaling pathway has emerged as a therapeutic target. Therefore, JAK inhib...
ORGANISM(S): Mus musculus 
2020-02-12 | E-MTAB-8536 | biostudies-arrayexpress
UnknownIs Thiourea the Weak Link? An Investigation of the In Vitro and In Vivo Destabilization of [<sup>203</sup>Pb]- and [<sup>212</sup>Pb]Pb<sup>2+</sup> Thiourea-Based Bioconjugates.
Not available
S-EPMC12921517 | biostudies-literature
TranscriptomicsMesenchymal stem cells from myelodysplastic syndromes are functionally and genomically abnormal
Myelodysplastic syndromes (MDS) are a group of clonal disorders of hematopoietic stem cells. Mesenchymal stem cells (MSC) are the progenitors of the Bone Marrow (BM) stroma and have been involved in the physiopathology of MDS. The presence of cytogenetic aberrations on MSC from MDS patients is contr...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-10822 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of Medulloblastoma
An observational experiment to RNA-seq profile 331 primary tumours from patients diagnosed with Medulloblastoma.
ORGANISM(S): Homo sapiens 
2022-09-01 | E-MTAB-10767 | biostudies-arrayexpress
TranscriptomicsCultured human adipose tissue pericytes and mesenchymal stromal cells display a very similar gene expression profile
Mesenchymal stromal cells (MSCs) are cultured cells that can give rise to mature mesenchymal cells under appropriate conditions, and secrete a number of biologically relevant molecules that may play an important role in regenerative medicine. Evidence indicates that pericytes (PCs) correspond to mes...
ORGANISM(S): Homo sapiens 
2015-07-22 | E-GEOD-67747 | biostudies-arrayexpress
TranscriptomicsHuman Bone Marrow Stromal Cells cultured on 3D nanofiber scaffolds or 2D films
Microarray analysis was used to evaluate expression differences from a single donor human bone marrow stromal cells (hBMSCs) as a function of varied polymer-based tissue engineering scaffolds. These scaffolds include polycaprolactone (PCL) nanofibers (PCL_NF), films (PCL_SC), poly D,L-lactic acid (...
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-50744 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of primary tumours derived from patients with medulloblastoma
An observational experiment to methylation profile 161 primary tumours from patients diagnosed with Medulloblastoma.
ORGANISM(S): Homo sapiens 
2022-11-01 | E-MTAB-10754 | biostudies-arrayexpress
UnknownUniversal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana.
Not available
S-EPMC6800102 | biostudies-literature
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